{"id":"W2792428989","doi":"10.2217/nnm-2018-0035","title":"Exosomes Derived From <i>Toxoplasma Gondii</i> Stimulate An Inflammatory Response Through JNK Signaling Pathway","year":2018,"lang":"en","type":"article","venue":"Nanomedicine","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation","funders":"","keywords":"Microvesicles; Toxoplasma gondii; Cell biology; p38 mitogen-activated protein kinases; Immune system; MAPK/ERK pathway; Innate immune system; Signal transduction; Kinase; Biology; Cell signaling; Immunology; microRNA; Antibody; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001360595,0.0003584654,0.0001853659,0.0001303056,0.0001699199,0.0003352437,0.0000871791,0.0002818572,0.001415877],"category_scores_gemma":[0.0001615028,0.0001017026,0.0004162941,0.0001045194,0.0001654267,0.0003704012,0.0002992121,0.0003459601,0.0003595179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001681749,"about_ca_system_score_gemma":0.0002041977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009340859,"about_ca_topic_score_gemma":0.0001127359,"domain_scores_codex":[0.9998765,0.00002165666,0.00001929441,0.00001975951,0.00002920342,0.00003357436],"domain_scores_gemma":[0.999922,0.00001349548,0.00002919782,0.000006281371,0.00001553897,0.00001352677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003097137,0.0000364309,0.0008590928,0.0002349144,0.00001151388,0.0003044135,0.00002734016,0.00004043917,0.9959995,0.0001253153,0.0001388041,0.001912516],"study_design_scores_gemma":[0.00004953697,0.0003302091,0.01147884,0.00004843127,0.00004034015,0.001688128,0.0001126725,0.000625459,0.9798589,0.0002204508,0.005538662,0.000008502412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989337,0.002943894,0.003341023,0.0003950793,0.0001476192,0.00005920944,0.0006549668,0.00006657503,0.003054563],"genre_scores_gemma":[0.9906418,0.002601034,0.002770548,0.0001879517,0.0000609972,0.00006164282,0.001207815,0.00002034925,0.002447815],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001415877,"threshold_uncertainty_score":0.004736602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02296942048463124,"score_gpt":0.28347992657848,"score_spread":0.2605105060938488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}