{"id":"W2792462695","doi":"10.1093/jcag/gwy008.187","title":"A186 INVESTIGATION OF THE PROTECTIVE ROLE OF MIR-122 AGAINST CELLULAR SENSORS OF RNA AT THE 5’ TERMINUS OF HEPATITIS C VIRUS GENOME","year":2018,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; McGill University","funders":"","keywords":"Protein kinase R; RNA; RNA silencing; Biology; Hepatitis C virus; microRNA; Virology; RIG-I; RNA virus; RNA interference; Cell biology; RNA-binding protein; Virus; Molecular biology; Protein kinase A; Kinase; Gene; Genetics; Mitogen-activated protein kinase kinase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000165749,0.0002391992,0.0001722999,0.0001662208,0.0001402923,0.0002737423,0.0001490616,0.0002577628,0.001004401],"category_scores_gemma":[0.0001288301,0.00007578831,0.0001880886,0.00009752978,0.0001538401,0.0002931388,0.0001140531,0.0002782593,0.0002405023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001829349,"about_ca_system_score_gemma":0.0001550366,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000121136,"about_ca_topic_score_gemma":0.0001385539,"domain_scores_codex":[0.9999306,0.00001396819,0.000005178681,0.00001496928,0.00002202916,0.00001329884],"domain_scores_gemma":[0.9999417,0.00001092669,0.00001371386,0.000005633908,0.00001308931,0.00001494926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002497279,0.00004713517,0.0004675429,0.0001749138,0.000009387111,0.00008185699,0.00001592176,0.00008347497,0.9889898,0.0003611679,0.0000818111,0.009437167],"study_design_scores_gemma":[0.00003513661,0.001979005,0.009568858,0.0000217116,0.00004765499,0.0008184272,0.00005669606,0.001822524,0.9727526,0.0003626612,0.01252274,0.00001197087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9452168,0.03963042,0.006045903,0.0005236518,0.0001981318,0.00006232219,0.0002819689,0.00007169806,0.007969047],"genre_scores_gemma":[0.9868429,0.007570128,0.002316389,0.0001644883,0.00006519895,0.00002382223,0.000291771,0.000007883535,0.002717328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001004401,"threshold_uncertainty_score":0.003360033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005272074070578024,"score_gpt":0.1859790338509451,"score_spread":0.180706959780367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}