{"id":"W2792676735","doi":"10.1016/j.ejps.2018.03.003","title":"Effects of dissolving microneedle fabrication parameters on the activity of encapsulated lysozyme","year":2018,"lang":"en","type":"article","venue":"European Journal of Pharmaceutical Sciences","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Ministry of Health, British Columbia","keywords":"Fabrication; Polymer; Microscale chemistry; Lysozyme; Dissolution; Materials science; Drug delivery; Nanotechnology; Chemistry; Chemical engineering; Composite material; Organic chemistry; Biochemistry; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003486447,0.0005861978,0.000279906,0.0002045836,0.0001560442,0.0005263767,0.0002626985,0.0005018756,0.001554471],"category_scores_gemma":[0.001665443,0.0003083075,0.0002287144,0.0002823629,0.0003115527,0.0007060707,0.0002470712,0.000466964,0.0003454832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002722711,"about_ca_system_score_gemma":0.0002556211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007596966,"about_ca_topic_score_gemma":0.001449166,"domain_scores_codex":[0.9995846,0.00005279077,0.00008228068,0.0001243193,0.00008508375,0.00007083729],"domain_scores_gemma":[0.9989175,0.0005701963,0.0002234092,0.00007866859,0.0001559405,0.00005431454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005544494,0.00006786803,0.0003047252,0.0001009771,0.0000108631,0.00005853029,0.00008541003,0.00017229,0.9953918,0.00003195746,0.00004966534,0.003171345],"study_design_scores_gemma":[0.000007959987,0.0002798347,0.001287281,0.00000653962,0.0000181924,0.0000206662,0.00003395071,0.000368476,0.9975836,0.00000894753,0.0003752277,0.000009328864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966893,0.001375815,0.0008509993,0.00005879092,0.00005353342,0.00001997037,0.0001815486,0.00004805671,0.0007218595],"genre_scores_gemma":[0.9943937,0.001086492,0.002304521,0.00007149299,0.00001496738,0.00003531695,0.0001744062,0.0000584663,0.001860642],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001554471,"threshold_uncertainty_score":0.005200207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1277248812420365,"score_gpt":0.4279553851724757,"score_spread":0.3002305039304392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}