{"id":"W2792798899","doi":"10.1038/s41375-018-0094-0","title":"Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study","year":2018,"lang":"en","type":"article","venue":"Leukemia","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; University of Toronto; BC Children's Hospital; Hospital for Sick Children; University of British Columbia; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Medicine; Refractory (planetary science); Lymphoblastic lymphoma; Lymphoma; Lymphoblastic Leukemia; Internal medicine; Leukemia; Salvage therapy; Retrospective cohort study; Oncology; Complete remission; Pediatrics; Bone marrow; Population; Childhood leukemia; Overall survival; Chemotherapy; Immunology; T cell; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000420123,0.0001935259,0.0002802518,0.0004431777,0.0002290009,0.0002817105,0.0001746692,0.0002030311,0.0004832764],"category_scores_gemma":[0.001006296,0.0001169498,0.0003176229,0.0005552825,0.0002262253,0.0002694632,0.0003140892,0.0003407848,0.0001262275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004744695,"about_ca_system_score_gemma":0.0003247156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00291855,"about_ca_topic_score_gemma":0.003452843,"domain_scores_codex":[0.9997452,0.00009076862,0.00002977479,0.0000395093,0.0000494189,0.00004530896],"domain_scores_gemma":[0.9993415,0.0000886344,0.0003590323,0.00005503225,0.00003727911,0.0001184438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002872508,0.00007707488,0.9967834,0.00001071249,0.00004095298,0.0002422355,0.00009262253,0.0001146306,0.000310557,0.00001975035,0.00008368451,0.001937234],"study_design_scores_gemma":[0.00004719514,0.0008416095,0.9964322,0.000007726542,0.00004748027,0.001569563,0.0002042608,0.0001611232,0.0002481961,0.00001691426,0.0004190893,0.000004518635],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994879,0.0001093401,0.00003360637,0.00001694775,0.000001159039,0.000007252953,0.0001885205,0.000001491152,0.0001538093],"genre_scores_gemma":[0.9993079,0.0001163103,0.00006510984,0.00001307977,0.000006211505,0.00001110239,0.0004295011,0.00000139501,0.00004949149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00291855,"threshold_uncertainty_score":0.005803108,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01337186297240948,"score_gpt":0.2868861352274389,"score_spread":0.2735142722550294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}