{"id":"W2792801522","doi":"10.1016/j.neubiorev.2018.03.011","title":"Chronobiological regulation of psychosocial and physiological outcomes in multiple sclerosis","year":2018,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University; Hotchkiss Brain Institute; University of Calgary; Western University; York University","funders":"","keywords":"Chronotherapy (sleep phase); Circadian rhythm; Chronobiology; Multiple sclerosis; Neuroscience; Disease; Immune system; Medicine; Melatonin; Mood; Psychosocial; Dark therapy; Experimental autoimmune encephalomyelitis; Psychology; Immunology; Psychiatry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005169846,0.0005831256,0.001118253,0.001090132,0.0001965393,0.0008367235,0.0005395457,0.000790703,0.001850817],"category_scores_gemma":[0.0009190032,0.0001566531,0.0003699086,0.001381918,0.0004156984,0.0005750596,0.0006750327,0.0009502902,0.0004370506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003905651,"about_ca_system_score_gemma":0.001188979,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002193168,"about_ca_topic_score_gemma":0.00422028,"domain_scores_codex":[0.9998573,0.00003104457,0.00002636956,0.00002769252,0.00004244091,0.00001521452],"domain_scores_gemma":[0.9997635,0.0001170179,0.00004865576,0.00000630498,0.00004795536,0.00001665398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001710215,0.00007910041,0.001103833,0.01566824,0.0002505013,0.0002192158,0.0001227606,0.0003222424,0.001456984,0.001879919,0.01233721,0.9663889],"study_design_scores_gemma":[0.0001029838,0.0003976042,0.02389316,0.01575529,0.001057294,0.002655094,0.0003654726,0.0002786648,0.0009663479,0.005496803,0.9489563,0.00007500949],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001720398,0.9993587,0.000046302,0.0001273296,0.00007131496,0.000001926994,0.00001018443,0.000002146167,0.0002100225],"genre_scores_gemma":[0.001637924,0.9977655,0.0001142733,0.00009677574,0.0001975579,0.000005542921,0.00001596661,6.257309e-7,0.000165716],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002193168,"threshold_uncertainty_score":0.006191611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4300619458443783,"score_gpt":0.4102939244286439,"score_spread":0.01976802141573442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}