{"id":"W2792877042","doi":"10.1038/s41418-017-0043-x","title":"Differential susceptibility of striatal, hippocampal and cortical neurons to Caspase-6","year":2018,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; McGill University; Montreal General Hospital; Jewish General Hospital","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; National Institute on Aging; Université Laval; Université de Montréal; Journal of Gastroenterology and Hepatology Foundation; Canadian Institutes of Health Research; Alzheimer Society; McGill University","keywords":"Neuroscience; Hippocampal formation; Neurodegeneration; Morris water navigation task; Striatum; Hippocampus; Microglia; Biology; Entorhinal cortex; Medicine; Internal medicine; Inflammation; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001853374,0.0002062908,0.0002548747,0.0004263265,0.0002268869,0.0005368899,0.0002182493,0.0003383679,0.002370804],"category_scores_gemma":[0.0003653811,0.0001463964,0.0003164668,0.0002315491,0.0002496792,0.0004214666,0.0003121,0.0006571703,0.0002544093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002929388,"about_ca_system_score_gemma":0.0002306628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001192892,"about_ca_topic_score_gemma":0.001248833,"domain_scores_codex":[0.9998336,0.00001376754,0.00001594831,0.00003343211,0.00003368215,0.00006948958],"domain_scores_gemma":[0.9998136,0.00002455392,0.00003594083,0.00002976419,0.00004209237,0.00005407144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008400507,0.00003399028,0.002546897,0.00005408506,0.00004263784,0.0001003247,0.00009632789,0.00008650758,0.9930989,0.0002795619,0.00004503814,0.002775746],"study_design_scores_gemma":[0.00004278601,0.0007926529,0.08487777,0.00001936513,0.00009182205,0.002545839,0.00055631,0.001089993,0.9074193,0.001045932,0.001499414,0.0000187432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971711,0.0008856994,0.0007469316,0.00006155507,0.00001530136,0.000006635622,0.0002254556,0.00001358144,0.0008737164],"genre_scores_gemma":[0.9977392,0.0004487567,0.0002637423,0.00002172583,0.000003226763,0.000007376815,0.0002381491,0.000005497182,0.001272317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002370804,"threshold_uncertainty_score":0.007931113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.030135033539372,"score_gpt":0.3016257240800443,"score_spread":0.2714906905406723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}