{"id":"W2792915401","doi":"10.1093/jcag/gwy009.084","title":"A84 INTERACTION OF SEROTONIN WITH PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-GAMMA IN ANTIMICROBIAL PEPTIDE PRODUCTION IN GUT","year":2018,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Enterochromaffin cell; Defensin; Peroxisome proliferator-activated receptor; Serotonin; Receptor; Biology; Internal medicine; Endocrinology; Tryptophan hydroxylase; Cell biology; 5-HT receptor; Chemistry; Biochemistry; Peptide; Medicine; Serotonergic","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001036309,0.0001889691,0.000203757,0.0001801365,0.0001056866,0.0002423042,0.0001306642,0.0003687622,0.0017441],"category_scores_gemma":[0.00007835692,0.0001509478,0.0003210008,0.00009326939,0.0002287308,0.0001564525,0.000151998,0.0005125505,0.0003444684],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002379899,"about_ca_system_score_gemma":0.0001118653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006553302,"about_ca_topic_score_gemma":0.0008421687,"domain_scores_codex":[0.999842,0.00002688414,0.00001286675,0.00003841808,0.00003527647,0.00004452565],"domain_scores_gemma":[0.9998915,0.00001480273,0.000032197,0.000009782348,0.0000122196,0.00003940978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003918625,0.00002051493,0.0006224771,0.0000454233,0.000005522067,0.0000758375,0.00001053325,0.00001627913,0.997708,0.00004002904,0.00002860111,0.001034981],"study_design_scores_gemma":[0.00007308253,0.001832508,0.09352604,0.00004031581,0.00006460635,0.0007169804,0.0001561507,0.0008304132,0.8993311,0.000122972,0.003294096,0.00001163303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910827,0.00525965,0.001475729,0.0003626773,0.00005597614,0.00001953343,0.000445449,0.00003514482,0.001263093],"genre_scores_gemma":[0.9932566,0.001848553,0.001139427,0.0002116428,0.00001796895,0.00004296998,0.0004289714,0.000007795679,0.003046126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0017441,"threshold_uncertainty_score":0.005834579,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005944141633761256,"score_gpt":0.2270519641420745,"score_spread":0.2211078225083132,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}