{"id":"W2793029599","doi":"10.1177/0022034518755688","title":"Smad6 Methylation Represses NFκB Activation and Periodontal Inflammation","year":2018,"lang":"en","type":"article","venue":"Journal of Dental Research","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Dental and Craniofacial Research; National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; Center for Strategic Scientific Initiatives, National Cancer Institute; National Institute of Child Health and Human Development; University of Southern California","keywords":"Proinflammatory cytokine; Inflammation; Cell biology; Signal transduction; Periodontitis; Chemokine; Biology; Immunology; Immune system; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002470218,0.0003419955,0.0002707137,0.0002334455,0.0002222408,0.0002804347,0.0002346391,0.0002858969,0.002893197],"category_scores_gemma":[0.000173247,0.0002108161,0.0004338577,0.0001094167,0.0002773855,0.0001794359,0.000291536,0.0008461258,0.0006579056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002018719,"about_ca_system_score_gemma":0.0003218542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004005901,"about_ca_topic_score_gemma":0.0008431684,"domain_scores_codex":[0.9997883,0.00003149341,0.00001862033,0.00005079859,0.00005485283,0.00005593406],"domain_scores_gemma":[0.9998829,0.00001271821,0.00004615932,0.00001482915,0.00001434406,0.0000291043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003633313,0.0000430519,0.0002799602,0.0001329272,0.00001350214,0.00004971635,0.00002869916,0.00007294121,0.9958974,0.0002375502,0.0001268745,0.002754003],"study_design_scores_gemma":[0.00004935413,0.0004414784,0.004081813,0.00002033462,0.00003944762,0.0003485568,0.00006292918,0.0007953769,0.9842933,0.000143363,0.009716052,0.000007985737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9717245,0.01177749,0.008515052,0.0006467754,0.0002974092,0.00005748076,0.0008393184,0.0003335599,0.005808449],"genre_scores_gemma":[0.9895232,0.003192998,0.00190106,0.0001470346,0.0000419605,0.00003880398,0.0006819724,0.00003888933,0.004433975],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002893197,"threshold_uncertainty_score":0.009678721,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03533186532842566,"score_gpt":0.3768937012248847,"score_spread":0.3415618358964591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}