{"id":"W2793041769","doi":"10.1139/cjm-2017-0609","title":"Plasmid persistence: costs, benefits, and the plasmid paradox","year":2018,"lang":"en","type":"review","venue":"Canadian Journal of Microbiology","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":255,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Plasmid; Biology; Horizontal gene transfer; Extrachromosomal DNA; Genetics; Experimental evolution; Persistence (discontinuity); Gene; Mobile genetic elements; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006576524,0.0003718304,0.001139135,0.000162821,0.0002014371,0.00006188218,0.0007735441,0.000694187,0.00008038441],"category_scores_gemma":[0.0002231625,0.0002128909,0.0004621741,0.00007254208,0.001620702,0.000003781743,0.00007802398,0.0004013695,0.00003370666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001156513,"about_ca_system_score_gemma":0.001733392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001457385,"about_ca_topic_score_gemma":0.004774874,"domain_scores_codex":[0.9980262,0.0003594088,0.0007224281,0.0003438945,0.00004114972,0.000506937],"domain_scores_gemma":[0.998422,0.00008879734,0.0005764657,0.0003933043,0.0001931726,0.0003262112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009962019,0.00007235216,0.000784662,0.006330156,0.006661619,0.0005167844,0.000616299,0.000004470555,0.005102742,0.001840699,0.4373393,0.5397347],"study_design_scores_gemma":[0.0005016839,0.0001934171,0.000005799945,0.001550967,0.0003501495,0.004855539,0.00005104931,8.718541e-8,0.0001672879,0.000007716238,0.9920666,0.0002496593],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005061866,0.9928905,0.00000600731,0.0001895392,0.001065413,0.0002697073,0.0002952956,0.000001377075,0.0002202289],"genre_scores_gemma":[0.001072001,0.9973071,0.0001416197,0.0002780255,0.0007146305,0.000002970017,0.0001995629,0.00004218685,0.000241866],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5547274,"threshold_uncertainty_score":0.868144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02120902287392276,"score_gpt":0.24416243617476,"score_spread":0.2229534133008372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}