{"id":"W2793060055","doi":"10.1093/annonc/mdy046.005","title":"MDICT consensus report: Recommendations regarding response criteria, endpoints and study designs for the development of immunotherapy combinations","year":2018,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Science, Research, and Medicine","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Partnership Against Cancer","funders":"","keywords":"Task force; Medicine; Cancer; Mandate; Targeted therapy; Internal medicine; Political science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.3220926,0.004210914,0.01299521,0.01055017,0.005440593,0.01104266,0.0214053,0.03403963,0.01142603],"category_scores_gemma":[0.4124024,0.005426637,0.02863819,0.00948002,0.004725352,0.006329072,0.01060618,0.03961062,0.01555017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01366473,"about_ca_system_score_gemma":0.05834609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01319098,"about_ca_topic_score_gemma":0.01591044,"domain_scores_codex":[0.7257173,0.1647271,0.06616922,0.006408544,0.03109781,0.005880019],"domain_scores_gemma":[0.4742512,0.2993198,0.03843737,0.01785294,0.1482908,0.0218479],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003413594,0.0007334435,0.002393012,0.02794611,0.002899875,0.0002569366,0.0007199814,0.001756935,0.001228715,0.007351214,0.7786855,0.1726148],"study_design_scores_gemma":[0.008170813,0.00116586,0.009371134,0.1144608,0.01123183,0.0005533244,0.0009087253,0.001852137,0.002969341,0.02800917,0.8206782,0.0006286164],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"methods","genre_scores_codex":[0.003411636,0.1183145,0.09056848,0.6114933,0.07546175,0.03579002,0.03082441,0.002596081,0.03153981],"genre_scores_gemma":[0.01243629,0.04405938,0.4853306,0.3452594,0.0150244,0.06389075,0.02018356,0.001554439,0.01226133],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.6779073,"threshold_uncertainty_score":0.8359805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.339398598336576,"score_gpt":0.5344369770478551,"score_spread":0.195038378711279,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}