{"id":"W2793069598","doi":"10.1093/jcag/gwy008.290","title":"A289 THE CROHN’S DISEASE-ASSOCIATED ADHERENT-INVASIVE E. COLIINDUCES MITOCHONDRIAL FRAGMENTATION IN ENTERIC EPITHELIUM THAT IS NOT DEPENDENT ON BACTERIAL SOLUBLE PRODUCTS OR MITOCHONDRIAL REACTIVE OXYGEN SPECIES","year":2018,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Mitochondrion; Biology; Cell biology; Mitochondrial fission; mitochondrial fusion; Mitochondrial apoptosis-induced channel; Fragmentation (computing); Reactive oxygen species; Cell; Bacterial outer membrane; Inner mitochondrial membrane; Mitochondrial DNA; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001219231,0.0003094955,0.000287221,0.0002013166,0.0001637881,0.0002818996,0.0001726196,0.0004543891,0.003455579],"category_scores_gemma":[0.0001196889,0.0001801169,0.0004122452,0.0001806939,0.000212219,0.0001928396,0.0002047287,0.001000627,0.0007592486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002454811,"about_ca_system_score_gemma":0.0002666819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008518878,"about_ca_topic_score_gemma":0.00115333,"domain_scores_codex":[0.9997784,0.0000311316,0.00002153742,0.00003915218,0.00007310322,0.00005659871],"domain_scores_gemma":[0.9998392,0.00002847677,0.00002698905,0.00002540406,0.00002462211,0.00005528358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002805894,0.0001297654,0.000191508,0.00004425467,0.000006615428,0.00008622342,0.00001499508,0.00002096132,0.9981377,0.00006349832,0.0001153702,0.0009084264],"study_design_scores_gemma":[0.0000882565,0.001577978,0.01899319,0.00002026532,0.00001908004,0.0007778354,0.0001058307,0.001247985,0.9718111,0.00009149976,0.005258866,0.000008092621],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932907,0.001006601,0.001346797,0.0002413946,0.0001076754,0.00003826256,0.000852221,0.00006699021,0.003049416],"genre_scores_gemma":[0.9860739,0.0008463645,0.002808895,0.0001681189,0.00001592203,0.0000709371,0.003232377,0.00002398647,0.006759493],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003455579,"threshold_uncertainty_score":0.01156008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02135598522779657,"score_gpt":0.2566840428574612,"score_spread":0.2353280576296646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}