{"id":"W2793322272","doi":"10.1093/jcag/gwy008.100","title":"A99 SYSTEMIC DELIVERY OF AN INHIBITOR OF MITOCHONDRIAL FISSION REDUCES THE SEVRITY OF CHEMICALLY-INDUCED COLITIS IN MICE","year":2018,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Mitochondrial fission; Colitis; Mitochondrion; mitochondrial fusion; Chemistry; Inflammatory bowel disease; Pharmacology; Inflammation; Context (archaeology); Medicine; Immunology; Biology; Disease; Biochemistry; Pathology; Mitochondrial DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002576603,0.0006570309,0.0006201708,0.0005267155,0.0002071427,0.000535399,0.0003736681,0.0008039837,0.002101265],"category_scores_gemma":[0.0002099566,0.0003534162,0.0004112331,0.0002510297,0.0005217352,0.0004966003,0.0002209524,0.002049339,0.0005863964],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003392067,"about_ca_system_score_gemma":0.000434493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007550497,"about_ca_topic_score_gemma":0.001195747,"domain_scores_codex":[0.9997261,0.0000308435,0.00003154808,0.00006413714,0.00005547897,0.0000917667],"domain_scores_gemma":[0.9996044,0.00003212764,0.0001348666,0.00002746928,0.00002504424,0.0001761336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00161434,0.0005977622,0.0001797888,0.00009846402,0.00001971447,0.00005918869,0.00003326314,0.0001294248,0.9939221,0.0001421239,0.0002358691,0.00296803],"study_design_scores_gemma":[0.0006122417,0.009944371,0.007181759,0.00007112617,0.0001035517,0.0004305215,0.000117808,0.002959993,0.9734637,0.0001582654,0.00493153,0.00002520883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910711,0.001736092,0.002646224,0.0005428019,0.0001727325,0.0001008985,0.0008870036,0.0005184428,0.002324746],"genre_scores_gemma":[0.987083,0.001589855,0.002539636,0.0002435793,0.00004479679,0.0001583271,0.001251893,0.00007370198,0.00701527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002101265,"threshold_uncertainty_score":0.007029474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007527348502804832,"score_gpt":0.2215639971772171,"score_spread":0.2140366486744122,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}