{"id":"W2793345208","doi":"10.1007/s00253-018-8753-7","title":"Inducer-independent production of pectinases in Aspergillus niger by overexpression of the D-galacturonic acid-responsive transcription factor gaaR","year":2018,"lang":"en","type":"article","venue":"Applied Microbiology and Biotechnology","topic":"Polysaccharides and Plant Cell Walls","field":"Agricultural and Biological Sciences","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada; BE-Basic Foundation; Genome Canada","keywords":"Aspergillus nidulans; Aspergillus niger; Catabolite repression; Inducer; Transcription (linguistics); Biochemistry; Catabolism; Gene; Chemistry; Biology; Enzyme; Molecular biology; Mutant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001216149,0.000128426,0.0002164581,0.00003341331,0.00009050853,0.000003041225,0.0002020763,0.000520509,0.0001096349],"category_scores_gemma":[0.00002734083,0.00004854243,0.00004161701,0.000205897,0.0004595174,0.00002660583,0.00008115053,0.0002264518,0.000003359723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001692774,"about_ca_system_score_gemma":0.0000100348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001452865,"about_ca_topic_score_gemma":0.000565203,"domain_scores_codex":[0.9991484,0.00006575536,0.0002336808,0.0003053084,0.00003738691,0.0002095172],"domain_scores_gemma":[0.9996454,0.00005675132,0.000168253,0.00008597795,0.00002698488,0.00001662573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001817028,0.00006279358,0.001075195,0.000006625591,0.00001074332,1.947857e-7,0.00009067664,1.142805e-7,0.9898055,0.0001964615,0.0001535709,0.008416426],"study_design_scores_gemma":[0.0001573828,0.0002482708,0.01844968,0.000024448,0.000007012394,0.00002591838,0.0001797925,5.21138e-7,0.9780099,0.0002046819,0.002601821,0.00009053853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981505,0.0003222311,0.000001418989,0.0009240902,0.0001635178,0.0002659302,0.0001099158,0.0000198395,0.00004259857],"genre_scores_gemma":[0.9996099,0.0001810903,0.00001281157,0.00007328961,0.00003368538,0.000006513234,0.00002557736,9.692521e-7,0.00005620288],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01737449,"threshold_uncertainty_score":0.4014643,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007957397016522086,"score_gpt":0.1855604610391743,"score_spread":0.1776030640226522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}