{"id":"W2793362907","doi":"10.1016/j.bpj.2019.01.016","title":"Gramicidin Increases Lipid Flip-Flop in Symmetric and Asymmetric Lipid Vesicles","year":2019,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Windsor","funders":"Oak Ridge National Laboratory; National Center for Advancing Translational Sciences; National Institute of General Medical Sciences; National Institute on Drug Abuse; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; U.S. Department of Energy","keywords":"Gramicidin; Chemistry; Vesicle; Lipid bilayer; Circular dichroism; Biophysics; Lipid bilayer phase behavior; Model lipid bilayer; Transmembrane protein; Crystallography; Membrane; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001656854,0.0002110722,0.0002718229,0.0002745888,0.00007501816,0.00008128749,0.0002120228,0.0001606286,0.00002486738],"category_scores_gemma":[0.0001034251,0.0001695799,0.0001289446,0.0005293303,0.0000659919,0.00001545848,0.0001217108,0.0002873201,0.00003354494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002348639,"about_ca_system_score_gemma":0.00006444375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004724869,"about_ca_topic_score_gemma":0.000007257947,"domain_scores_codex":[0.9987283,0.00008913313,0.0002811968,0.0003342979,0.0002201888,0.000346882],"domain_scores_gemma":[0.9993795,0.00003565215,0.0001095455,0.0002179273,0.00006282855,0.0001945732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008264449,0.0001510151,0.01971986,0.00001431845,0.00002157344,0.00001142651,0.00001172786,0.000003219388,0.9568847,0.0001398499,0.0001898037,0.02276989],"study_design_scores_gemma":[0.001531177,0.0006700556,0.1607702,0.00003342173,0.00004399257,0.0001902518,0.00007258104,0.00004428787,0.832768,0.00003662404,0.003486396,0.0003529896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987657,0.0001388782,0.00001411023,0.0000893666,0.0004100684,0.000138368,0.000009807169,0.000008959026,0.0004247151],"genre_scores_gemma":[0.9972324,0.0003360961,0.0002029793,0.0002852084,0.001730755,0.000003575932,0.00001824637,0.00002434762,0.0001663673],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1410503,"threshold_uncertainty_score":0.6915267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007334464619864704,"score_gpt":0.2364185135466149,"score_spread":0.2290840489267502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}