{"id":"W2793373964","doi":"10.1038/s41467-018-03490-8","title":"Physiological and therapeutic regulation of glucose homeostasis by upper small intestinal PepT1-mediated protein sensing","year":2018,"lang":"en","type":"article","venue":"Nature Communications","topic":"Diet and metabolism studies","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Diabetes Canada; University of Toronto; Toronto General Hospital","funders":"Banting and Best Diabetes Centre, University of Toronto; Canadian Institutes of Health Research; University of Toronto; Diabetes Canada","keywords":"Glucose homeostasis; Homeostasis; Small intestine; Glucose transporter; Insulin; Internal medicine; Transporter; Endocrinology; Biology; Insulin resistance; Casein; Chemistry; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002015752,0.0004466405,0.0003234445,0.0002094667,0.0001232512,0.0003271636,0.0002202039,0.000313754,0.0009945707],"category_scores_gemma":[0.0001353832,0.00009354675,0.0002157527,0.0001270931,0.0003367621,0.0003771945,0.0002097333,0.0009743483,0.0001636521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000171436,"about_ca_system_score_gemma":0.0001579481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001026111,"about_ca_topic_score_gemma":0.0001969062,"domain_scores_codex":[0.9999315,0.00001421421,0.000004923848,0.00001447503,0.00001680697,0.00001816429],"domain_scores_gemma":[0.9999124,0.00001225964,0.00003088725,0.000008482257,0.000007064672,0.00002895698],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001600565,0.0003211705,0.0004047087,0.0002032561,0.00001791063,0.00009097304,0.00001138852,0.00009451079,0.9804242,0.0002801384,0.0001483276,0.01640297],"study_design_scores_gemma":[0.0002000521,0.006935964,0.01102245,0.00003428204,0.00008257526,0.000631312,0.00004328138,0.0008338001,0.9739336,0.0003225613,0.005946142,0.0000139896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9769554,0.01243519,0.006969663,0.0006119125,0.0001619837,0.00008369971,0.0002131926,0.0001493193,0.002419713],"genre_scores_gemma":[0.98739,0.006827009,0.004068426,0.0001471521,0.0000659204,0.00005566359,0.0002340677,0.00002101348,0.001190695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009945707,"threshold_uncertainty_score":0.003327131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03881567782592947,"score_gpt":0.3082830856863513,"score_spread":0.2694674078604218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}