{"id":"W2793415258","doi":"10.1615/intjmedmushrooms.2018025400","title":"Extrinsic and Intrinsic Apoptotic Responses Induced by Shiitake Culinary-Medicinal Mushroom Lentinus edodes (Agaricomycetes) Aqueous Extract against a Larynx Carcinoma Cell Line","year":2018,"lang":"en","type":"article","venue":"International journal of medicinal mushrooms","topic":"Fungal Biology and Applications","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Apoptosis; Lentinus; Flow cytometry; Cell growth; Reactive oxygen species; Cell cycle; Mushroom; Biology; Cell; Cell culture; Chemistry; Biochemistry; Cell biology; Molecular biology; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006531087,0.0002367379,0.0001744989,0.0002188307,0.0001046897,0.0001013155,0.00006381131,0.0001078101,0.000945966],"category_scores_gemma":[0.00005491566,0.00004680343,0.0001578587,0.0001510965,0.00008212151,0.0000832091,0.0001083743,0.000211257,0.0001094644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008035912,"about_ca_system_score_gemma":0.0001133707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005711502,"about_ca_topic_score_gemma":0.000981343,"domain_scores_codex":[0.9999491,0.00001055774,0.000007462688,0.000007657472,0.0000115897,0.00001357767],"domain_scores_gemma":[0.9999647,0.000009036205,0.000007856903,0.000003870419,0.00000711351,0.000007402794],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002092525,0.00005706261,0.000650239,0.00007312409,0.000007391105,0.00007904669,0.00002624258,0.00002930555,0.9968807,0.00001886776,0.00002445487,0.001944437],"study_design_scores_gemma":[0.00002355216,0.001258228,0.03281916,0.00001505091,0.00005025193,0.0003474967,0.00009258024,0.0003399167,0.9637792,0.00002730525,0.001243778,0.000003542744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958463,0.002301899,0.000505174,0.00004694512,0.00001300266,0.00001886151,0.0002526308,0.00002258192,0.0009925319],"genre_scores_gemma":[0.9955064,0.001852675,0.0006405134,0.00004505992,0.00001019533,0.00002786124,0.0004468661,0.000002668155,0.001467788],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000945966,"threshold_uncertainty_score":0.00316453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02038703888030668,"score_gpt":0.2989961176654821,"score_spread":0.2786090787851754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}