{"id":"W2793449736","doi":"10.1016/j.antiviral.2018.02.017","title":"Inhibition of NF-κB-dependent HIV-1 replication by the marine natural product bengamide A","year":2018,"lang":"en","type":"article","venue":"Antiviral Research","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"AIDS Vancouver; Jewish General Hospital; McGill University; University of British Columbia; Université de Sherbrooke; Simon Fraser University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Viral replication; Long terminal repeat; Peripheral blood mononuclear cell; NF-κB; Reporter gene; HIV Long Terminal Repeat; Gene; Virology; Cell culture; Gene expression; Molecular biology; Cell biology; Signal transduction; In vitro; Genetics; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001033337,0.0003147279,0.0001171497,0.0001315891,0.0001501131,0.0002029142,0.000229007,0.0001478613,0.002284822],"category_scores_gemma":[0.0001235254,0.00009418818,0.0002160697,0.00006779087,0.0002341061,0.0002003024,0.0002000543,0.0004218044,0.0002955823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002510405,"about_ca_system_score_gemma":0.0002774986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001139533,"about_ca_topic_score_gemma":0.00116111,"domain_scores_codex":[0.9999542,0.000007921396,0.000002999852,0.000005246069,0.000008070101,0.00002156808],"domain_scores_gemma":[0.9999546,0.00001056954,0.000009712945,0.000006379656,0.00000504968,0.00001380702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007266711,0.00007598667,0.0001626993,0.00006675842,0.000009382507,0.00009503953,0.00001875702,0.0001480572,0.993041,0.0002429237,0.0001163699,0.005296427],"study_design_scores_gemma":[0.00007797644,0.001201198,0.001989327,0.000008943876,0.00001386254,0.00017616,0.0000325835,0.0004449059,0.993137,0.0001068544,0.002805003,0.000006184226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880741,0.004235666,0.0014874,0.0002116621,0.00008143812,0.00003353245,0.000215221,0.00007967795,0.005581327],"genre_scores_gemma":[0.9952807,0.001763789,0.0004647643,0.00003422654,0.00001909162,0.00001161356,0.0001184543,0.000006400622,0.002300958],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002284822,"threshold_uncertainty_score":0.007643521,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03573369459454651,"score_gpt":0.3503164268284042,"score_spread":0.3145827322338577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}