{"id":"W2793459189","doi":"10.1002/stem.2783","title":"Concise Review: Human Induced Pluripotent Stem Cell Models of Retinitis Pigmentosa","year":2018,"lang":"en","type":"review","venue":"Stem Cells","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Instituto de Salud Carlos III; Institute of Infection and Immunity; Grantová Agentura České Republiky","keywords":"Biology; Retinitis pigmentosa; Induced pluripotent stem cell; Stem cell; Cell biology; Genetics; Embryonic stem cell; Neuroscience; Retina; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003793362,0.0005878812,0.001485514,0.00009074186,0.000077197,0.00002267163,0.0005920926,0.0005000141,0.0000666437],"category_scores_gemma":[0.000002968364,0.0005053534,0.000674155,0.0001720042,0.00009834534,0.00000489888,0.0003032713,0.000191656,0.0001017219],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003727775,"about_ca_system_score_gemma":0.0003268917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008946461,"about_ca_topic_score_gemma":0.000003386653,"domain_scores_codex":[0.9970818,0.0002630135,0.001155769,0.0007536085,0.0003447399,0.000401128],"domain_scores_gemma":[0.997907,0.0000186507,0.0009164095,0.000817597,0.0001929805,0.0001472943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004688942,0.0003351831,0.000005499246,0.2385747,0.0007130922,0.00003713613,0.0001499139,0.000001602557,0.01715077,0.00009291393,0.1431077,0.5997846],"study_design_scores_gemma":[0.0002741806,0.00030042,1.226163e-7,0.01768967,0.000436218,0.000007117155,0.00003922038,6.618765e-7,0.01577902,0.0000126838,0.9648784,0.0005823066],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004982037,0.9833903,0.00003343924,0.000007069772,0.0003027841,0.001385179,0.00008758517,0.00001442097,0.014281],"genre_scores_gemma":[0.0003150351,0.9922002,0.00007129716,0.000113698,0.0001359107,0.0001107525,0.0004489904,0.0000846398,0.006519508],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8217707,"threshold_uncertainty_score":0.9997398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05034552271222298,"score_gpt":0.2951013967966003,"score_spread":0.2447558740843773,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}