{"id":"W2793475561","doi":"10.1111/mmi.13947","title":"A <i>Toxoplasma gondii</i> locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions","year":2018,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Canada Research Chairs; National Institutes of Health; National Science Foundation","keywords":"Biology; Genetics; Locus (genetics); Gene; Mitochondrial DNA; Toxoplasma gondii; Mutant; Eukaryote; Mitochondrion; Cell biology; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003584689,0.0003119304,0.0004833714,0.0001702672,0.0006773435,0.00002292517,0.0004577023,0.0003838028,0.0001440979],"category_scores_gemma":[0.0006131981,0.0002322417,0.0002697051,0.0002942225,0.002133903,0.00006393142,0.000219879,0.0002670229,0.0002630038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007568545,"about_ca_system_score_gemma":0.0001166244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001319756,"about_ca_topic_score_gemma":0.0005692078,"domain_scores_codex":[0.9977778,0.0003615314,0.0004923448,0.0005617027,0.00003380552,0.0007727863],"domain_scores_gemma":[0.9979631,0.0008051877,0.0002445783,0.0005936771,0.0003630296,0.00003037375],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007949961,0.0001020585,0.0008173081,0.00002464705,0.0006013731,0.000004559549,0.000243258,0.00002540048,0.9855293,0.0004644027,0.01089388,0.0004988262],"study_design_scores_gemma":[0.00239276,0.0009270757,0.00100196,0.00002329928,0.0001206676,0.0001150004,0.0002040903,0.00003814082,0.7945971,0.0001034917,0.200233,0.0002434358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9416081,0.005012708,0.04220606,0.002905286,0.003234844,0.002726736,0.001198482,0.0001961706,0.0009116456],"genre_scores_gemma":[0.9959272,0.00003286698,0.000700991,0.0002027644,0.0001019327,0.0002665223,0.0006245305,0.00003934038,0.002103865],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1909322,"threshold_uncertainty_score":0.9470543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02749189776175714,"score_gpt":0.2634462976946421,"score_spread":0.235954399932885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}