{"id":"W2793506398","doi":"10.3934/microbiol.2018.1.173","title":"Novel roles for two-component regulatory systems in cytotoxicity and virulence-related &lt;em&gt;properties in Pseudomonas aeruginosa&lt;/em&gt;","year":2018,"lang":"en","type":"article","venue":"AIMS Microbiology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Killam Trusts; Cystic Fibrosis Canada","keywords":"Pseudomonas aeruginosa; Virulence; Component (thermodynamics); Microbiology; Cytotoxicity; Biology; Virulence factor; Chemistry; Bacteria; Gene; Genetics; In vitro; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004576701,0.0003336154,0.0004759561,0.0001383839,0.0001173825,0.00004226808,0.0002083329,0.0005382219,0.000006625799],"category_scores_gemma":[0.00005478315,0.0002974089,0.00008769395,0.0001120922,0.0004188581,0.00001224756,0.0002074182,0.0001450219,0.00001059244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005203353,"about_ca_system_score_gemma":0.00007149448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001854085,"about_ca_topic_score_gemma":0.002023971,"domain_scores_codex":[0.9979082,0.0001438374,0.0005778396,0.0007268666,0.00004568053,0.0005975713],"domain_scores_gemma":[0.9992289,0.00002687275,0.0001810785,0.0003721009,0.0001123436,0.00007872899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003690857,0.0001132419,0.0005928078,0.00003892824,0.00005069731,0.000003592818,0.0002340694,0.00002609875,0.9977089,0.0001867807,0.0001998068,0.000476019],"study_design_scores_gemma":[0.002581948,0.0005328719,0.005563779,0.0001564835,0.00001910986,0.000226967,0.0001653572,0.0002865005,0.9839543,0.00001660504,0.006013563,0.0004825095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996119,0.002345124,0.0000552697,0.0001127566,0.0005890452,0.0005954609,0.0001033964,0.00002275046,0.00005725333],"genre_scores_gemma":[0.9985131,0.0001078544,0.0004481741,0.0002417778,0.0002875865,0.00003429365,0.0002010732,0.0000376904,0.0001284684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01375457,"threshold_uncertainty_score":0.9999478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01056946484860604,"score_gpt":0.2142469860302844,"score_spread":0.2036775211816783,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}