{"id":"W2793588309","doi":"10.1093/jcag/gwy009.279","title":"A279 COLONIZATION WITH PROTEOLYTIC BACTERIA INDUCES LOW-GRADE INFLAMMATION AND BARRIER DYSFUNCTION IN MICE","year":2018,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Proteases; Microbiology; Biology; Proteolytic enzymes; Colitis; Neutrophil elastase; Immunity; Protease; Immunology; Inflammation; Immune system; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005046006,0.001432381,0.0007128732,0.001957175,0.0004795456,0.000823529,0.0007467446,0.001318761,0.002251468],"category_scores_gemma":[0.000344017,0.0008324034,0.0009700805,0.0005441938,0.0008808144,0.0006335648,0.0006641652,0.002219453,0.001320776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008335591,"about_ca_system_score_gemma":0.000617343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0011468,"about_ca_topic_score_gemma":0.001604761,"domain_scores_codex":[0.9989662,0.0001573424,0.00008541057,0.0002392606,0.0002201053,0.0003317316],"domain_scores_gemma":[0.9987987,0.0001063962,0.0003543477,0.0001257375,0.00005308101,0.000561676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001388657,0.0008610587,0.0005280759,0.00005934288,0.00002135944,0.0001982443,0.00005628515,0.0001037833,0.9952595,0.0001647695,0.0001545244,0.001204445],"study_design_scores_gemma":[0.0007535084,0.01993164,0.02383723,0.0001026669,0.0001182433,0.00190184,0.0003131175,0.003428636,0.943867,0.0004538635,0.005234304,0.00005780835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938493,0.001038068,0.001613386,0.0002973382,0.00005759252,0.0001067978,0.0009627752,0.0002666861,0.001808028],"genre_scores_gemma":[0.9859832,0.001366355,0.003180197,0.0004137685,0.00004991765,0.0002646813,0.001741487,0.0001653185,0.006835083],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002251468,"threshold_uncertainty_score":0.007531941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006041232566429514,"score_gpt":0.1796208612836687,"score_spread":0.1735796287172392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}