{"id":"W2793819196","doi":"10.1002/cbic.201800049","title":"An RNA‐Cleaving Catalytic DNA Accelerated by Freezing","year":2018,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; China Sponsorship Council","keywords":"Deoxyribozyme; Chemistry; RNA; Cleavage (geology); DNA; Divalent; Biophysics; Catalysis; Biochemistry; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002045391,0.0003935841,0.0002358971,0.0001236391,0.00007402914,0.0001956109,0.0002641321,0.0002294198,0.0008534832],"category_scores_gemma":[0.000383512,0.0001708329,0.00025797,0.00009218154,0.0001822467,0.0001851622,0.0001544343,0.0004128914,0.0002362838],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001818892,"about_ca_system_score_gemma":0.0001175668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003937004,"about_ca_topic_score_gemma":0.000309215,"domain_scores_codex":[0.9998572,0.00002571752,0.00001296877,0.00003947907,0.00004259259,0.00002209399],"domain_scores_gemma":[0.9997711,0.00007482455,0.00006266785,0.00002772316,0.00003287588,0.00003082724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002003766,0.000003258247,0.00005415043,0.0000131531,0.000002512985,0.00001807659,0.000006896065,0.00005624195,0.9991822,0.0000127828,0.000004978773,0.0006257553],"study_design_scores_gemma":[0.000001788538,0.00006238857,0.0004340836,0.000001615747,0.000002848763,0.0000476819,0.000002795542,0.0002611523,0.9989225,0.000006278037,0.0002552758,0.000001637994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852831,0.0007129549,0.01303217,0.00004204968,0.00002712095,0.00003825554,0.0001337066,0.0000899927,0.0006406289],"genre_scores_gemma":[0.9887345,0.0003304335,0.008920391,0.0000323158,0.000008570114,0.00002743627,0.0002517947,0.00003668865,0.001657663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008534832,"threshold_uncertainty_score":0.002855182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01276778222490125,"score_gpt":0.2852477162333957,"score_spread":0.2724799340084944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}