{"id":"W2793932483","doi":"10.1128/aac.02519-17","title":"Enhanced Ex Vivo Plasmodium vivax Intraerythrocytic Enrichment and Maturation for Rapid and Sensitive Parasite Growth Assays","year":2018,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Malaria Research and Control","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Government of Canada; National Institute of Allergy and Infectious Diseases; Ministério da Ciência, Tecnologia e Inovação; Bill and Melinda Gates Foundation; Howard Hughes Medical Institute","keywords":"Ex vivo; Plasmodium vivax; Parasite hosting; Biology; In vivo; Plasmodium (life cycle); Malaria; Plasmodium falciparum; Microbiology; Apicomplexa; Virology; Immunology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004564562,0.0004935302,0.0002614798,0.0001644659,0.0001480945,0.0002822283,0.0002847589,0.0002368967,0.001195861],"category_scores_gemma":[0.0002807391,0.0001960656,0.0001477246,0.0001727767,0.0001861272,0.0002280737,0.0002779491,0.0005583083,0.0005942689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001993336,"about_ca_system_score_gemma":0.0001457098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004448233,"about_ca_topic_score_gemma":0.001018929,"domain_scores_codex":[0.9997146,0.0000917078,0.0000260113,0.00005171928,0.00008277023,0.00003315269],"domain_scores_gemma":[0.9998012,0.00005972892,0.00004404819,0.00002817294,0.00005011667,0.00001673711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002845934,0.00001183557,0.00006356394,0.00001981666,0.000001221311,0.00001108925,0.00001067624,0.00006803701,0.9991263,0.00004084594,0.00003284775,0.0005853735],"study_design_scores_gemma":[0.000005842795,0.0001758247,0.001302045,0.00000419484,0.00000703826,0.0001030573,0.000007860309,0.001564793,0.994218,0.00003092991,0.002575142,0.000005267599],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7644078,0.001783489,0.2238041,0.0002590275,0.00008864519,0.0005230318,0.002405914,0.0008702392,0.00585783],"genre_scores_gemma":[0.8501968,0.001331246,0.1362081,0.000153607,0.00002657934,0.0006335563,0.002893068,0.0001964478,0.00836054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001195861,"threshold_uncertainty_score":0.004000485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0108295700207738,"score_gpt":0.2694990357274163,"score_spread":0.2586694657066425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}