{"id":"W2793932483","doi":"10.1128/aac.02519-17","title":"Enhanced Ex Vivo Plasmodium vivax Intraerythrocytic Enrichment and Maturation for Rapid and Sensitive Parasite Growth Assays","year":2018,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Malaria Research and Control","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Government of Canada; National Institute of Allergy and Infectious Diseases; Ministério da Ciência, Tecnologia e Inovação; Bill and Melinda Gates Foundation; Howard Hughes Medical Institute","keywords":"Ex vivo; Plasmodium vivax; Parasite hosting; Biology; In vivo; Plasmodium (life cycle); Malaria; Plasmodium falciparum; Microbiology; Apicomplexa; Virology; Immunology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001500138,0.0001767029,0.0002790931,0.00006277597,0.0001760378,0.00008025805,0.0000311245,0.00009728397,0.00007509872],"category_scores_gemma":[0.00002210381,0.0001430836,0.00003949669,0.00005965012,0.0001749084,0.00009678665,0.00002501486,0.00008683489,0.000003963234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002554127,"about_ca_system_score_gemma":0.00003574101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003344247,"about_ca_topic_score_gemma":0.00001039269,"domain_scores_codex":[0.9990307,0.00002799644,0.0001677748,0.0003364416,0.000116024,0.0003210595],"domain_scores_gemma":[0.9994935,0.00004989585,0.00006041918,0.0001023315,0.0001468336,0.0001470565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004839608,0.0001554742,0.0005216241,0.0001954668,0.0002863776,0.00001141844,0.001240744,5.693828e-8,0.9590594,0.0004879309,0.01506989,0.01813197],"study_design_scores_gemma":[0.01552133,0.002018398,0.05095937,0.0001624557,0.0001340242,0.0001463798,0.0001841517,0.00168576,0.9205306,0.0002686742,0.008007706,0.0003812191],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837303,0.00004501518,0.006179227,0.008490395,0.00008633988,0.0009335215,0.0000284553,0.00002668152,0.000480054],"genre_scores_gemma":[0.989922,0.00174811,0.0008644158,0.006615219,0.0003307648,0.00001548573,0.00002463765,0.00002122527,0.0004581366],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05043774,"threshold_uncertainty_score":0.5834778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0108295700207738,"score_gpt":0.2694990357274163,"score_spread":0.2586694657066425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}