{"id":"W2793988400","doi":"10.1016/j.tetlet.2018.03.039","title":"A practical microwave method for the synthesis of fluoromethy 4-methylbenzenesulfonate in tert-amyl alcohol","year":2018,"lang":"en","type":"article","venue":"Tetrahedron Letters","topic":"Fluorine in Organic Chemistry","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cancer Research UK; Institute of Cancer Research; University of Hull; Univerzita Karlova v Praze","keywords":"Chemistry; Methylene; Reagent; Fluorine; Alcohol; Yield (engineering); Nucleophilic aromatic substitution; Microwave; Combinatorial chemistry; Nucleophilic substitution; Organic chemistry; Nucleophile","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002633983,0.000413339,0.0002067832,0.0004209793,0.0002579486,0.0001009464,0.0002661782,0.0002936253,0.003918202],"category_scores_gemma":[0.0001518401,0.0001623912,0.0002099536,0.0003451627,0.0001518778,0.0002719134,0.0001986456,0.000635428,0.002230402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000176184,"about_ca_system_score_gemma":0.000317985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003806059,"about_ca_topic_score_gemma":0.001291174,"domain_scores_codex":[0.9998764,0.00001701229,0.00001608901,0.00002872983,0.00003591434,0.00002591826],"domain_scores_gemma":[0.9999382,0.00001195942,0.00002186057,0.00001033866,0.000009280194,0.000008385987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008458023,0.00004915585,0.0001666074,0.0002913181,0.00001059658,0.0002444709,0.0000839952,0.0002056655,0.9800483,0.000793495,0.0004696171,0.01755204],"study_design_scores_gemma":[0.00004196307,0.001201189,0.001977422,0.00003063696,0.00003325249,0.001567868,0.00004186179,0.0008246381,0.9518214,0.0003022137,0.04212463,0.00003284478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.5943242,0.01976104,0.3493818,0.00111876,0.0005334546,0.000778712,0.001599464,0.002225611,0.03027695],"genre_scores_gemma":[0.8978465,0.01051381,0.07777628,0.0001812116,0.000121246,0.0003753339,0.001102926,0.0001352308,0.01194754],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.003918202,"threshold_uncertainty_score":0.01310772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1161193085936636,"score_gpt":0.4638931922827743,"score_spread":0.3477738836891107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}