{"id":"W2794076195","doi":"10.1016/j.bbadis.2018.02.008","title":"The G protein-coupled P2Y6 receptor promotes colorectal cancer tumorigenesis by inhibiting apoptosis","year":2018,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Azoxymethane; Apoptosis; XIAP; Cancer research; Colorectal cancer; Carcinogenesis; Protein kinase B; Cancer; Chemistry; Biology; Internal medicine; Medicine; Programmed cell death; Caspase; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002327306,0.0004527456,0.000332576,0.0000621826,0.0003662613,0.00009356697,0.0005967892,0.0001569374,0.00004019892],"category_scores_gemma":[0.0002561698,0.0003681615,0.0003798579,0.0003468946,0.0005059774,0.00001682923,0.0003053293,0.0001415792,0.00001176121],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003110705,"about_ca_system_score_gemma":0.0003453855,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009476286,"about_ca_topic_score_gemma":0.000004075052,"domain_scores_codex":[0.99752,0.0002099405,0.0004979103,0.0007713745,0.0004348927,0.0005658717],"domain_scores_gemma":[0.9983253,0.00004025445,0.0004079075,0.0005665511,0.000344491,0.0003154298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006906572,0.0002708688,0.00003075519,0.00006183064,0.0002682926,0.000001428514,0.00005131901,0.000002758533,0.9926588,0.00005435621,0.005668554,0.0002403824],"study_design_scores_gemma":[0.0005491109,0.0004764129,0.0002675148,0.0001078255,0.0001672922,6.935668e-7,0.0000580127,0.00009374736,0.9970743,0.00005393982,0.0006731949,0.0004779292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946992,0.001662632,0.0001352589,0.002184226,0.0001282937,0.0007496229,0.0003054781,0.00004220149,0.00009308191],"genre_scores_gemma":[0.9976501,0.00026361,0.000355586,0.0003383086,0.0005056229,0.0003259002,0.0003230713,0.00009638933,0.0001413487],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004995359,"threshold_uncertainty_score":0.999877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00576370236298099,"score_gpt":0.2424647538793183,"score_spread":0.2367010515163374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}