{"id":"W2794092996","doi":"10.1074/jbc.h118.002088","title":"Skin cells prefer a slower calcium pump","year":2018,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genetic and rare skin diseases.","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Heart and Stroke Foundation of Canada","keywords":"Calcium; Transporter; Gene isoform; Mutation; Calcium metabolism; Mechanism (biology); Cell biology; Darier's disease; Chemistry; Biology; Disease; Biochemistry; Medicine; Gene; Internal medicine; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000189887,0.0003230405,0.0004103681,0.0003167227,0.0003832121,0.001168756,0.0003143034,0.001001751,0.005753093],"category_scores_gemma":[0.0004470948,0.0002428438,0.0004246688,0.0002741074,0.000352035,0.0008503724,0.0005405739,0.001331101,0.003670487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003112766,"about_ca_system_score_gemma":0.0001721154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006427998,"about_ca_topic_score_gemma":0.0008015197,"domain_scores_codex":[0.9996988,0.0000335976,0.00002479842,0.00008254953,0.0001048028,0.00005561089],"domain_scores_gemma":[0.999569,0.00005596292,0.00007188277,0.00008698428,0.0001426733,0.00007353978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001810566,0.00002079473,0.0009083386,0.00007425113,0.00001225494,0.000836374,0.00007144401,0.00004612473,0.9883555,0.001308562,0.001588873,0.006596461],"study_design_scores_gemma":[0.0001798429,0.0007494337,0.03661045,0.0000838314,0.0001213575,0.02934808,0.001322506,0.001728407,0.7573436,0.003974367,0.1684063,0.0001318733],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8966445,0.01806298,0.01952087,0.008398213,0.003891187,0.0001255665,0.001107864,0.001218037,0.05103084],"genre_scores_gemma":[0.9464029,0.005124313,0.009594646,0.004490329,0.0004591895,0.00006129555,0.0008333561,0.0002553555,0.03277865],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005753093,"threshold_uncertainty_score":0.01924604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01696214466859518,"score_gpt":0.2583606787073413,"score_spread":0.2413985340387461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}