{"id":"W2794093079","doi":"10.1073/pnas.1712061115","title":"Solution NMR structure of yeast Rcf1, a protein involved in respiratory supercomplex formation","year":2018,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Knut och Alice Wallenbergs Stiftelse; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Dimer; Chemistry; Crystallography; Helix (gastropod); Helix bundle; Protein structure; Nuclear magnetic resonance spectroscopy; Transmembrane domain; Salt bridge; Molecular dynamics; Transmembrane protein; Biophysics; Stereochemistry; Membrane; Biochemistry; Computational chemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001218831,0.0003014487,0.0002384187,0.0002692701,0.0004191993,0.0003164641,0.0004762441,0.0004530555,0.001242562],"category_scores_gemma":[0.0003268004,0.0001422204,0.0001617591,0.0003255072,0.0002229234,0.0003269802,0.0001356455,0.0006874265,0.000301765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008823503,"about_ca_system_score_gemma":0.0003276586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00554772,"about_ca_topic_score_gemma":0.00399803,"domain_scores_codex":[0.9999619,0.000004003747,0.000002188656,0.00001492859,0.000009187911,0.000007845491],"domain_scores_gemma":[0.9998348,0.00002787541,0.00004252244,0.00001090132,0.00003906196,0.00004473968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007748704,0.0002069134,0.00324789,0.0002981639,0.00004811608,0.0006934993,0.0004414868,0.004168067,0.9750289,0.001602199,0.003381886,0.01010787],"study_design_scores_gemma":[0.0003066854,0.00136078,0.09095513,0.0001402657,0.0002955567,0.002157917,0.001266095,0.07136726,0.7694811,0.00250629,0.05994707,0.0002158431],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883981,0.003434441,0.002882034,0.001060362,0.00006930637,0.00002145882,0.001344137,0.0001844126,0.002605678],"genre_scores_gemma":[0.9846631,0.001849211,0.004198955,0.000195812,0.00004023106,0.00001707628,0.006983278,0.00004634296,0.002006026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00554772,"threshold_uncertainty_score":0.01103085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0448687732487383,"score_gpt":0.2938170209824488,"score_spread":0.2489482477337105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}