{"id":"W2794105314","doi":"10.1002/bies.201700095","title":"Surviving Starvation: AMPK Protects Germ Cell Integrity by Targeting Multiple Epigenetic Effectors","year":2018,"lang":"en","type":"review","venue":"BioEssays","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"AMPK; Epigenetics; Biology; Caenorhabditis elegans; Cell biology; Chromatin; Phenotype; Protein kinase A; Regulator; Germ cell; Starvation; Genetics; Gene; Kinase; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001079918,0.0008699195,0.0011635,0.0001153745,0.0002895976,0.0001374865,0.0008016638,0.001095064,0.00006873435],"category_scores_gemma":[0.000554256,0.0007779397,0.0005318875,0.0002280429,0.0002224946,0.000006579432,0.0004354729,0.0006077954,0.0001380383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009073544,"about_ca_system_score_gemma":0.0003563014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001725167,"about_ca_topic_score_gemma":0.00009200062,"domain_scores_codex":[0.996145,0.0006660863,0.0008467541,0.001239959,0.0003658945,0.0007362719],"domain_scores_gemma":[0.997727,0.0001215788,0.0007063027,0.0009874169,0.0002292156,0.0002284985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001172855,0.001961892,0.004939198,0.1099603,0.001905399,0.00005383627,0.001524305,0.00004131165,0.1596317,0.00003814813,0.195144,0.5246827],"study_design_scores_gemma":[0.0002886347,0.0003149879,0.00001881259,0.000972598,0.0002287044,0.000007523005,0.00002711121,0.00002817573,0.02957851,0.00001671372,0.9675171,0.001001129],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00416521,0.9862464,0.006156974,0.00001199776,0.00103246,0.001733262,0.0002526886,0.0000726741,0.0003283338],"genre_scores_gemma":[0.01333805,0.9791065,0.00258638,0.00006252923,0.001426423,0.0002408513,0.002198157,0.0002223906,0.0008186426],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7723731,"threshold_uncertainty_score":0.9994671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02782659456535637,"score_gpt":0.2806200884471704,"score_spread":0.252793493881814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}