{"id":"W2794120560","doi":"10.1093/jcag/gwy008.094","title":"A93 POST-INDUCTION INFLIXIMAB TROUGH LEVELS VARY WIDELY AND AID IN INDIVIDUALIZING INFLIXIMAB MAINTENANCE THERAPY FOR PEDIATRIC IBD","year":2018,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Medicine; Infliximab; Ulcerative colitis; Internal medicine; Regimen; Concomitant; Trough level; Inflammatory bowel disease; Gastroenterology; Maintenance therapy; Surgery; Disease; Chemotherapy; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002045024,0.0002359767,0.0006294825,0.0003549962,0.0001870228,0.0007813333,0.0002356954,0.000284152,0.001411185],"category_scores_gemma":[0.003553466,0.0001156841,0.0003492088,0.000606033,0.0001771227,0.0004430732,0.0002282602,0.0007417628,0.0002934861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003684774,"about_ca_system_score_gemma":0.000314369,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004781078,"about_ca_topic_score_gemma":0.001048846,"domain_scores_codex":[0.9990068,0.0002679077,0.0001547172,0.0001226556,0.000341837,0.0001061834],"domain_scores_gemma":[0.9974551,0.001032577,0.001024524,0.0001330178,0.0001875933,0.0001672463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005214386,0.0003771508,0.7908633,0.0002601344,0.0001973049,0.0004272957,0.0002562531,0.0006711575,0.01750094,0.0001622817,0.0009212908,0.1831485],"study_design_scores_gemma":[0.0001014261,0.003676742,0.9879444,0.00004402179,0.00009757947,0.0008232535,0.00006382103,0.0003781911,0.004510601,0.00005982551,0.002292586,0.000007621761],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990106,0.005959213,0.001246738,0.0001411475,0.00001908951,0.00006070859,0.0002814224,0.0000349487,0.00215071],"genre_scores_gemma":[0.9967474,0.00102115,0.001349118,0.0001019936,0.00002132666,0.00004747192,0.0004193746,0.00001017735,0.0002820183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9995219,"threshold_uncertainty_score":0.0108152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01079574316110717,"score_gpt":0.2358977035074102,"score_spread":0.225101960346303,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}