{"id":"W2794146536","doi":"10.1007/s40257-018-0352-y","title":"Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison","year":2018,"lang":"en","type":"article","venue":"American Journal of Clinical Dermatology","topic":"Dermatologic Treatments and Research","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lynde Centre for Dermatology; Windsor Clinical Research; Occupational Cancer Research Centre; Western University; Innovaderm (Canada)","funders":"Galderma","keywords":"Medicine; Acne; Tolerability; Benzoyl peroxide; Dermatology; Adapalene; Acne scars; Randomized controlled trial; Clinical trial; Scars; Surgery; Internal medicine; Adverse effect","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001777726,0.0002524448,0.004059944,0.0003734599,0.00006421645,0.00001531084,0.0001475567,0.0001913316,0.00001386559],"category_scores_gemma":[0.001003522,0.0001341569,0.0002916736,0.0003989992,0.002622083,0.0001590793,0.00004615969,0.0006007958,6.292986e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003663521,"about_ca_system_score_gemma":0.000954995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001433929,"about_ca_topic_score_gemma":0.0001252127,"domain_scores_codex":[0.9939069,0.001883046,0.002932571,0.0003239496,0.000597977,0.0003556005],"domain_scores_gemma":[0.9947344,0.001302114,0.002909961,0.0002250922,0.0006011079,0.000227313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9656544,0.001360113,0.0166253,0.00005521331,0.001344058,0.00034934,0.0005645474,0.0001275256,0.000221179,0.00001124174,0.00003064131,0.0136564],"study_design_scores_gemma":[0.950298,0.02270777,0.01095318,0.0005789118,0.001222717,0.00867477,0.001235541,0.003134224,0.0009553832,0.00006914794,0.00001095551,0.0001594025],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996722,0.0002305102,0.0003306911,0.001002487,0.0001679865,0.001445635,0.000008669718,0.000006573019,0.00008539692],"genre_scores_gemma":[0.9939173,0.0003253425,0.005481933,0.00003752725,0.0001718023,0.00001273739,0.000005536767,0.00001985649,0.00002795348],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02134765,"threshold_uncertainty_score":0.9661175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06676159548000438,"score_gpt":0.4059407479291471,"score_spread":0.3391791524491428,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}