{"id":"W2794146536","doi":"10.1007/s40257-018-0352-y","title":"Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison","year":2018,"lang":"en","type":"article","venue":"American Journal of Clinical Dermatology","topic":"Dermatologic Treatments and Research","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lynde Centre for Dermatology; Windsor Clinical Research; Occupational Cancer Research Centre; Western University; Innovaderm (Canada)","funders":"Galderma","keywords":"Medicine; Acne; Tolerability; Benzoyl peroxide; Dermatology; Adapalene; Acne scars; Randomized controlled trial; Clinical trial; Scars; Surgery; Internal medicine; Adverse effect","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001977243,0.0007137219,0.002005108,0.0004750138,0.0003070544,0.000529486,0.0006584072,0.0009342997,0.002322944],"category_scores_gemma":[0.0009703374,0.0003900004,0.001254272,0.0003117432,0.000624411,0.0004254322,0.0002446668,0.001245103,0.0002927043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002232052,"about_ca_system_score_gemma":0.0004774887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004719635,"about_ca_topic_score_gemma":0.0008810196,"domain_scores_codex":[0.9993284,0.0003523296,0.00006049739,0.00009475553,0.00008461718,0.00007944501],"domain_scores_gemma":[0.9992515,0.0002353728,0.0001847327,0.00006220436,0.00007222489,0.0001939606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8544886,0.03898673,0.002451889,0.001736264,0.001506937,0.00007406309,0.0001690434,0.000355334,0.03716407,0.00007011944,0.000378783,0.06261808],"study_design_scores_gemma":[0.4661037,0.5122322,0.01542816,0.00006705468,0.001088278,0.00007561496,0.00006240666,0.0004873164,0.0038656,0.00006260313,0.0005089632,0.00001827918],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946563,0.003733263,0.0002906256,0.00008185986,0.0000790114,0.0006943359,0.0001080457,0.00003224685,0.0003244234],"genre_scores_gemma":[0.995207,0.002161053,0.00095968,0.0001656654,0.0001754041,0.0006920494,0.0001411528,0.000009279387,0.0004887427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002322944,"threshold_uncertainty_score":0.0104568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06676159548000438,"score_gpt":0.4059407479291471,"score_spread":0.3391791524491428,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}