{"id":"W2794215802","doi":"10.1177/1535370217750087","title":"Liquid biopsy and its role in an advanced clinical trial for lung cancer","year":2018,"lang":"en","type":"review","venue":"Experimental Biology and Medicine","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; U.S. Food and Drug Administration; Hamilton Health Sciences Foundation; Arkansas Research Alliance; U.S. Department of Health and Human Services","keywords":"Liquid biopsy; Lung cancer; Medicine; Biopsy; Cancer; Clinical trial; Lung; Oncology; Pathology; Internal medicine; Intensive care medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003058841,0.0002740068,0.0008818398,0.00005802908,0.00005847894,0.000004845796,0.0001231217,0.0005357568,0.0000215125],"category_scores_gemma":[0.0001458339,0.000207626,0.00009236061,0.00003994016,0.0002954778,0.000002952777,0.000125086,0.0001215113,4.495913e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002294783,"about_ca_system_score_gemma":0.0001323907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000198409,"about_ca_topic_score_gemma":0.00003693897,"domain_scores_codex":[0.9984779,0.0001001225,0.000520517,0.0006359363,0.00002982778,0.0002356988],"domain_scores_gemma":[0.9993623,0.00008971264,0.0001802946,0.000188432,0.00003175743,0.0001474989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.06744019,0.001203019,0.0004424348,0.003959248,0.0009720337,0.00001978019,0.000718698,5.470918e-7,0.07173637,0.001332137,0.004788376,0.8473872],"study_design_scores_gemma":[0.0193258,0.01075353,0.000004907358,0.0009111371,0.0001766751,0.00001594534,0.00009320754,0.00001395911,0.001181426,0.00001055299,0.9671853,0.0003275328],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1148556,0.8827969,0.000005428717,0.00003464253,0.001090644,0.001048373,0.0001221255,0.000004154381,0.00004218429],"genre_scores_gemma":[0.005583492,0.9900283,0.00008678497,0.0002381345,0.002738384,0.0005478928,0.0006913487,0.00002762235,0.00005808887],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9623969,"threshold_uncertainty_score":0.8466743,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05617502694842571,"score_gpt":0.4819052148206509,"score_spread":0.4257301878722252,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}