{"id":"W2794254072","doi":"10.1093/jcag/gwy008.092","title":"A91 NOVEL TRIM22 INTERACTIONS REVEAL POTENTIAL CAUSATIVE MECHANISMS IN VERY EARLY ONSET INFLAMMATORY BOWEL DISEASE (VEOIBD)","year":2018,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"NOD2; Ubiquitin ligase; Biology; KRAS; Ubiquitin; Cancer research; Exome sequencing; Phenotype; Mutation; Genetics; Immune system; Innate immune system; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002667865,0.0004865139,0.0003931256,0.001035995,0.0004228266,0.0005341488,0.0002966501,0.0007710566,0.006206481],"category_scores_gemma":[0.0006731107,0.0002209311,0.0006095233,0.0006646079,0.0001934203,0.0002706664,0.0004677195,0.0004757833,0.001571919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002415709,"about_ca_system_score_gemma":0.0001039176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007034896,"about_ca_topic_score_gemma":0.001043266,"domain_scores_codex":[0.999778,0.0000279378,0.00002702423,0.00008128159,0.00004529527,0.00004042538],"domain_scores_gemma":[0.9997436,0.00006250915,0.00007644406,0.00003249588,0.0000237861,0.00006117829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003623796,0.0002082677,0.1682802,0.0008570399,0.0006421424,0.05504689,0.0006272636,0.0008576261,0.6802357,0.001529836,0.007022464,0.08106878],"study_design_scores_gemma":[0.0001497036,0.0007342702,0.6343394,0.000308759,0.0008290696,0.161515,0.000526796,0.005626641,0.1504413,0.00275173,0.04268346,0.00009392834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841774,0.004981789,0.003370932,0.0002749967,0.00006455111,0.00003282407,0.003075219,0.0003787773,0.003643639],"genre_scores_gemma":[0.9898962,0.0009184508,0.003746748,0.000332793,0.00003704429,0.00002167957,0.002971504,0.00006407195,0.002011511],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006206481,"threshold_uncertainty_score":0.02076274,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005345485722503209,"score_gpt":0.2071141493560748,"score_spread":0.2017686636335716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}