{"id":"W2794328684","doi":"10.1159/000487346","title":"Does Endothelin-1 Raise or Lower Blood Pressure in Humans?","year":2018,"lang":"en","type":"article","venue":"The Nephron journals/Nephron journals","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Internal medicine; Endothelin 1; Endocrinology; Endothelin receptor; Vasodilation; Endothelins; Vascular smooth muscle; Prostacyclin; Endothelium; Nitric oxide; Receptor; Smooth muscle","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001469335,0.0007182641,0.002409971,0.001004567,0.0003303325,0.00130887,0.001002018,0.002604846,0.003490619],"category_scores_gemma":[0.004050195,0.0002501445,0.0006379508,0.001409696,0.0009193477,0.0018917,0.0006994304,0.00297105,0.002104242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005883499,"about_ca_system_score_gemma":0.001323865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009400338,"about_ca_topic_score_gemma":0.001054132,"domain_scores_codex":[0.9994314,0.0001149981,0.0001412896,0.0001382623,0.0001378961,0.00003616488],"domain_scores_gemma":[0.9980773,0.0008215409,0.0002418782,0.00004112136,0.0007028238,0.0001154035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0003258223,0.00004661286,0.0007682131,0.03867306,0.0004553757,0.0003334798,0.0001808089,0.0001070951,0.0007529228,0.003319891,0.226862,0.7281747],"study_design_scores_gemma":[0.00008746533,0.0001674761,0.003171628,0.01485041,0.0005206385,0.002012989,0.0002277032,0.0000654425,0.0003634059,0.002704032,0.9757745,0.00005435546],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.0000421064,0.9952515,0.00002168107,0.00270946,0.0018169,0.000001250057,0.00001470679,0.000002891946,0.0001394957],"genre_scores_gemma":[0.0008288536,0.9904851,0.00004582138,0.003386492,0.004894116,0.000006751419,0.00002976018,0.000003401045,0.0003196032],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003490619,"threshold_uncertainty_score":0.01167732,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02573099171843819,"score_gpt":0.3142799199177769,"score_spread":0.2885489281993387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}