{"id":"W2794347665","doi":"10.1016/j.bpc.2018.01.002","title":"Biophysical evidence for differential gallated green tea catechins binding to membrane type-1 matrix metalloproteinase and its interactors","year":2018,"lang":"en","type":"article","venue":"Biophysical Chemistry","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Montréal","funders":"Université du Québec à Montréal","keywords":"Chemistry; Matrix metalloproteinase; Naringenin; Biochemistry; Cell biology; Transmembrane protein; Endoplasmic reticulum; Proteolysis; Catechin; Intracellular; Flavonoid; Enzyme; Polyphenol; Receptor; Biology; Antioxidant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001619389,0.0002278036,0.0001746209,0.0001515414,0.0003243848,0.0004158149,0.0003195245,0.0003154781,0.001509689],"category_scores_gemma":[0.0003227561,0.0001939955,0.0002766433,0.0001397452,0.0002737796,0.0003421365,0.0002603098,0.0006230732,0.0002823852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003334952,"about_ca_system_score_gemma":0.0001153169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008358804,"about_ca_topic_score_gemma":0.0008824441,"domain_scores_codex":[0.9998257,0.00002890657,0.000009814408,0.00004822186,0.00003387816,0.00005359878],"domain_scores_gemma":[0.9998054,0.00005463376,0.0000389392,0.0000389513,0.00003146126,0.00003063393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009457534,0.00000832315,0.0002174143,0.00001250036,0.000006419743,0.00002105573,0.00001669996,0.00001468079,0.9992827,0.0001367465,0.00001751195,0.0001715083],"study_design_scores_gemma":[0.00001285379,0.00004469294,0.01323222,0.000002337668,0.00002369806,0.0001538372,0.00005076003,0.0005906145,0.9848605,0.0001396265,0.0008837422,0.000005019596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939492,0.001181921,0.003291345,0.0002715043,0.00002800179,0.000008807878,0.0001475912,0.00003970099,0.001081962],"genre_scores_gemma":[0.9976178,0.0002975378,0.0007933697,0.00009018021,0.00000905908,0.00001030363,0.000171789,0.00001096226,0.0009989481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001509689,"threshold_uncertainty_score":0.005050421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02555054912245369,"score_gpt":0.3055650427645373,"score_spread":0.2800144936420836,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}