{"id":"W2794351657","doi":"10.1139/y99-132","title":"Heterotrimeric G proteins in heart disease","year":2000,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Heterotrimeric G protein; G protein; G protein-coupled receptor; G beta-gamma complex; Biology; GTPase-activating protein; GTP-binding protein regulators; Cell biology; G protein-coupled receptor kinase; Signal transduction","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003223292,0.0003158718,0.0004707676,0.0005202144,0.0003824328,0.0005195056,0.0003834288,0.00099607,0.004536945],"category_scores_gemma":[0.0003038458,0.00006844101,0.0001543475,0.0006144257,0.0007783896,0.0003674315,0.0005774728,0.00121605,0.001403581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008511782,"about_ca_system_score_gemma":0.001107601,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00498593,"about_ca_topic_score_gemma":0.006244901,"domain_scores_codex":[0.999876,0.00002308821,0.000009435013,0.00001881709,0.00004914308,0.00002349245],"domain_scores_gemma":[0.9999144,0.00001687024,0.00001102422,0.000005255114,0.00002416693,0.00002824675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005929706,0.0001735288,0.004516619,0.002409516,0.00009562329,0.002996151,0.0005536632,0.0006296505,0.01981564,0.05426038,0.1667541,0.7472022],"study_design_scores_gemma":[0.0001008866,0.0001758627,0.02658249,0.001235401,0.0001046795,0.009254764,0.00035488,0.000305588,0.001679344,0.03853844,0.9216425,0.00002502336],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.007368773,0.9452621,0.001159521,0.01891483,0.002911467,0.000023708,0.0001069477,0.00007733153,0.02417536],"genre_scores_gemma":[0.09272429,0.8684091,0.001570548,0.007376462,0.003990554,0.00002942159,0.0002575751,0.0000204324,0.02562159],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.00498593,"threshold_uncertainty_score":0.01517761,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008346955708737213,"score_gpt":0.2491749129026753,"score_spread":0.240827957193938,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}