{"id":"W2794358105","doi":"10.1038/nature26156","title":"Modular assembly of the nucleolar pre-60S ribosomal subunit","year":2018,"lang":"en","type":"article","venue":"Nature","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":157,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Robertson Foundation","keywords":"Ribosome; Ribosomal RNA; Eukaryotic Ribosome; Ribosomal protein; Eukaryotic Small Ribosomal Subunit; Cell biology; Protein subunit; Biology; Ribosome biogenesis; Eukaryotic Large Ribosomal Subunit; RNA; Chemistry; Biophysics; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002205391,0.0003252014,0.0001773252,0.0002153219,0.0002358127,0.0004384717,0.0002630589,0.0002530695,0.0008911238],"category_scores_gemma":[0.0001859181,0.0002304379,0.0003112045,0.0001373269,0.0002424514,0.0003625716,0.0003840232,0.0004646154,0.0006307317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004863307,"about_ca_system_score_gemma":0.0002957786,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004485796,"about_ca_topic_score_gemma":0.001111675,"domain_scores_codex":[0.9998845,0.00001029152,0.000005876819,0.00002897799,0.00003238789,0.00003794474],"domain_scores_gemma":[0.9998935,0.00001012471,0.00002317692,0.0000237879,0.00001345312,0.00003596476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000954747,0.00001578741,0.0003256227,0.00002834183,0.000006133643,0.00009399845,0.00002247969,0.0003217625,0.9924543,0.002115955,0.0001685144,0.004351566],"study_design_scores_gemma":[0.00002099144,0.0001936783,0.01006895,0.00001240302,0.0000262608,0.0004887227,0.00006152123,0.004269173,0.9715215,0.001835089,0.01148121,0.000020571],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837961,0.001456401,0.01026582,0.0002274156,0.00007153249,0.00002347811,0.0001653011,0.0004021027,0.003591868],"genre_scores_gemma":[0.9887381,0.0006007832,0.006943496,0.00005556201,0.00002463901,0.00001359527,0.0004695262,0.00006660558,0.00308776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008911238,"threshold_uncertainty_score":0.003528595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004796351441971974,"score_gpt":0.2523959261060488,"score_spread":0.2475995746640769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}