{"id":"W2794798563","doi":"10.1186/s12940-018-0357-2","title":"A review of the experimental evidence on the toxicokinetics of carbon monoxide: the potential role of pathophysiology among susceptible groups","year":2018,"lang":"en","type":"review","venue":"Environmental Health","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Centre for Disease Control; Health Canada; Wilfrid Laurier University; Douglas College","funders":"Health Canada","keywords":"Carboxyhemoglobin; Medicine; Disease; Carbon monoxide poisoning; Intensive care medicine; CO poisoning; Toxicodynamics; Hemoglobin; Environmental health; Poison control; Internal medicine; Toxicokinetics; Carbon monoxide; Toxicity","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006514422,0.0003664806,0.0009207487,0.00002488164,0.000100218,0.000003291599,0.0008367482,0.0002205565,0.00004942856],"category_scores_gemma":[0.00004789991,0.0001888469,0.0006421075,0.0001128014,0.0007489064,0.00000281808,0.0004721,0.0002714721,0.000003571562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008698791,"about_ca_system_score_gemma":0.0001812361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001029171,"about_ca_topic_score_gemma":0.0000112225,"domain_scores_codex":[0.9970294,0.0009676398,0.0009208822,0.0004392003,0.0003300309,0.0003128367],"domain_scores_gemma":[0.9973904,0.00007007066,0.001159698,0.001293561,0.00001176532,0.00007447178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001745957,0.001361121,0.0002206947,0.04971225,0.0006114788,0.000002831991,0.0005208545,0.000012314,0.7667349,0.0001309068,0.004925514,0.1755926],"study_design_scores_gemma":[0.0008001225,0.01026008,0.001671987,0.1353005,0.001107894,0.00006040843,0.00159012,0.00003572907,0.4788994,0.0001181465,0.3686957,0.001459867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.08999939,0.9083483,0.000001528023,0.00007152199,0.0001389678,0.001258,0.0001015744,0.000002174507,0.00007853379],"genre_scores_gemma":[0.1532349,0.8458796,0.00001764366,0.0004681129,0.0001592922,0.00009514258,0.00005180962,0.00003843798,0.00005506519],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.3637702,"threshold_uncertainty_score":0.7700951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01791141076947278,"score_gpt":0.2866318220319741,"score_spread":0.2687204112625013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}