{"id":"W2794812256","doi":"10.1016/j.ebiom.2018.03.028","title":"Trans-Fats Inhibit Autophagy Induced by Saturated Fatty Acids","year":2018,"lang":"en","type":"article","venue":"EBioMedicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Labex Immuno-Oncology; European Research Council; BioTechMed-Graz; Institut National Du Cancer; Institut Universitaire de France; Institute of Cancer Research; Labex; Ligue Contre le Cancer; Agence Nationale de la Recherche; Fondation ARC pour la Recherche sur le Cancer; Cancer Research Institute; Bundesministerium für Wissenschaft, Forschung und Wirtschaft; Fondation pour la Recherche Médicale; Association pour la Recherche sur le Cancer; Seerave Foundation; Fondation Leducq; European Commission; Institut Mérieux; Austrian Science Fund","keywords":"Elaidic acid; Autophagy; Palmitic acid; Saturated fatty acid; Fatty acid; Oleic acid; Biochemistry; Peroxisome; Unsaturated fatty acid; Chemistry; Biology; Endoplasmic reticulum; Linoleic acid; Gene; Apoptosis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002200947,0.0003175953,0.0005237574,0.0002164448,0.0001409336,0.00001468906,0.0001618826,0.0002496661,0.002762204],"category_scores_gemma":[0.00005808459,0.0002397738,0.000116034,0.0007518889,0.0004163893,0.0001040053,0.00002490319,0.0003152982,0.0002934581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008492117,"about_ca_system_score_gemma":0.0001518831,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004909821,"about_ca_topic_score_gemma":0.000003022957,"domain_scores_codex":[0.9980462,0.00005156209,0.0004336743,0.0004577979,0.0005091839,0.0005016172],"domain_scores_gemma":[0.9986684,0.00004025595,0.00009781377,0.0005223353,0.0001900838,0.0004811344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006139641,0.0003268871,0.0006034322,0.0000524599,0.0002123471,0.0001311875,0.0008718303,1.581419e-8,0.9514038,0.00006086711,0.02496292,0.02076029],"study_design_scores_gemma":[0.01135225,0.00346886,0.06516363,0.0003395742,0.0003016728,0.000128594,0.0001919888,0.0001362529,0.8141306,0.0003397006,0.1040096,0.0004372665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855179,0.001526286,0.0007049216,0.004413292,0.0007541665,0.0005196146,0.00003597407,0.0003648188,0.006163047],"genre_scores_gemma":[0.989818,0.00008657375,0.0002300492,0.006113003,0.001466569,0.00002381738,0.0002910827,0.00005588701,0.001915018],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1372732,"threshold_uncertainty_score":0.9981494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01727925116431737,"score_gpt":0.2974125586034351,"score_spread":0.2801333074391177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}