{"id":"W2794812256","doi":"10.1016/j.ebiom.2018.03.028","title":"Trans-Fats Inhibit Autophagy Induced by Saturated Fatty Acids","year":2018,"lang":"en","type":"article","venue":"EBioMedicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Labex Immuno-Oncology; European Research Council; BioTechMed-Graz; Institut National Du Cancer; Institut Universitaire de France; Institute of Cancer Research; Labex; Ligue Contre le Cancer; Agence Nationale de la Recherche; Fondation ARC pour la Recherche sur le Cancer; Cancer Research Institute; Bundesministerium für Wissenschaft, Forschung und Wirtschaft; Fondation pour la Recherche Médicale; Association pour la Recherche sur le Cancer; Seerave Foundation; Fondation Leducq; European Commission; Institut Mérieux; Austrian Science Fund","keywords":"Elaidic acid; Autophagy; Palmitic acid; Saturated fatty acid; Fatty acid; Oleic acid; Biochemistry; Peroxisome; Unsaturated fatty acid; Chemistry; Biology; Endoplasmic reticulum; Linoleic acid; Gene; Apoptosis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001548193,0.0003131318,0.0002811369,0.0002383785,0.0001238568,0.0001698238,0.0001446909,0.0002156036,0.001234065],"category_scores_gemma":[0.0001542311,0.0000856712,0.0002307561,0.0001539512,0.0001800629,0.0001300783,0.0002571766,0.0003556293,0.000319487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001296171,"about_ca_system_score_gemma":0.0002124066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006936438,"about_ca_topic_score_gemma":0.001527617,"domain_scores_codex":[0.9998752,0.00003045598,0.00002105086,0.00001603617,0.00002394552,0.00003325688],"domain_scores_gemma":[0.9999032,0.00002501467,0.00001741338,0.00001198753,0.0000187737,0.00002354281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009105179,0.00006067457,0.0002665252,0.00008201405,0.00001492532,0.00003711138,0.0000214926,0.00005850334,0.9965127,0.00005342382,0.0000319087,0.001950125],"study_design_scores_gemma":[0.00003414896,0.0006381195,0.002135322,0.00001224623,0.00002307646,0.00009955524,0.00004361574,0.0003150463,0.9951179,0.00003580842,0.001542439,0.0000026868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947004,0.002870354,0.0009292034,0.00006428162,0.00002866589,0.00001554084,0.0002253359,0.00003332648,0.001132749],"genre_scores_gemma":[0.9938532,0.002343231,0.001219427,0.0000741246,0.00001419626,0.00002988345,0.0004117578,0.00001284114,0.002041382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001234065,"threshold_uncertainty_score":0.004128337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01727925116431737,"score_gpt":0.2974125586034351,"score_spread":0.2801333074391177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}