{"id":"W2794916125","doi":"10.1002/hep.29903","title":"Hepatocyte microvesicle levels improve prediction of mortality in patients with cirrhosis","year":2018,"lang":"en","type":"article","venue":"Hepatology","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Instituto de Salud Carlos III; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Agence Nationale de la Recherche; Canadian Association for the Study of the Liver","keywords":"Cirrhosis; Medicine; Hepatocyte; Liver disease; Internal medicine; Gastroenterology; Chronic liver disease; Microvesicle; Portal hypertension; Portal venous pressure; Microvesicles; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000118296,0.0001316319,0.000181951,0.00005023758,0.00003023604,0.000004113226,0.0001547399,0.0001609833,0.00003376058],"category_scores_gemma":[0.00005172912,0.0001252625,0.00004778562,0.0001060011,0.00029776,0.000006231515,0.00009020902,0.00006584059,0.000008653063],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002166815,"about_ca_system_score_gemma":0.00008085424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009655258,"about_ca_topic_score_gemma":0.0002023257,"domain_scores_codex":[0.9989279,0.00008432476,0.0002784362,0.0003613929,0.000106697,0.0002412304],"domain_scores_gemma":[0.9991863,0.00000752483,0.0001301684,0.0004596726,0.0001507158,0.00006565094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002175342,0.0001891446,0.784464,0.00001736045,0.00003725237,0.00000220092,0.0000259459,5.045221e-7,0.2143602,0.000029754,0.0001205183,0.000535575],"study_design_scores_gemma":[0.001047296,0.0005790918,0.6301003,0.000006882498,0.00002012576,0.000001488153,0.000006912107,0.0001183483,0.3675272,0.00006283719,0.0004393144,0.00009021515],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984359,0.00010344,0.0005256147,0.00001573652,0.0001432005,0.0002547063,0.000161409,0.00001071064,0.0003492537],"genre_scores_gemma":[0.9991898,0.000007107782,0.0004452504,0.000114932,0.00006980626,0.00002019,0.00009382226,0.00002039788,0.00003872037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1543637,"threshold_uncertainty_score":0.5108055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01061332235140714,"score_gpt":0.2364367644733529,"score_spread":0.2258234421219458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}