{"id":"W2794943680","doi":"10.1007/978-3-319-67932-7_9","title":"Resistance to Inhibitors of Angiogenesis","year":2018,"lang":"en","type":"book-chapter","venue":"Resistance to targeted anti-cancer therapeutics","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"University of Toronto","keywords":"Angiogenesis; Stromal cell; Cancer research; Blockade; Downregulation and upregulation; Metastasis; Vascular endothelial growth factor; Medicine; Tumor progression; Biology; Cancer; Receptor; VEGF receptors; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002367702,0.0005166193,0.0003338617,0.0005877214,0.0001824913,0.0008457945,0.0002875126,0.0005351857,0.005585654],"category_scores_gemma":[0.0003299369,0.0001802673,0.0002607614,0.0003621865,0.0003239086,0.0005123961,0.0003720848,0.001486625,0.002410393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005598392,"about_ca_system_score_gemma":0.0002679464,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000296301,"about_ca_topic_score_gemma":0.000384866,"domain_scores_codex":[0.9998118,0.00002974518,0.000008166402,0.00003690153,0.00008259997,0.0000307076],"domain_scores_gemma":[0.9999185,0.00002964419,0.00001662908,0.000008897855,0.00001564784,0.00001063418],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002566549,0.0003151019,0.0007086323,0.0008551402,0.00005403807,0.0007802285,0.0001971062,0.001924822,0.1876215,0.08630195,0.07778095,0.6432039],"study_design_scores_gemma":[0.00004133707,0.0003399155,0.0007195112,0.0001698562,0.00002662279,0.003696775,0.00002566141,0.0009414556,0.06218357,0.007835131,0.9240035,0.00001673555],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.06303603,0.4060778,0.02296435,0.01144705,0.002426374,0.0002406379,0.0007815374,0.0007844924,0.4922418],"genre_scores_gemma":[0.3365895,0.2541059,0.007065671,0.006286622,0.00121376,0.000320077,0.001119108,0.0002014107,0.393098],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.005585654,"threshold_uncertainty_score":0.01868582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02174723499077049,"score_gpt":0.2760519939831697,"score_spread":0.2543047589923992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}