{"id":"W2794949547","doi":"10.3389/fgene.2018.00117","title":"Efficient Gene Transfer and Gene Editing in Sterlet (Acipenser ruthenus)","year":2018,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Beijing Academy of Agricultural and Forestry Sciences; National Natural Science Foundation of China; University of Ottawa","keywords":"Transcription activator-like effector nuclease; CRISPR; Biology; Genome editing; Cas9; Gene; Nuclease; Guide RNA; Mutant; Genetics; Molecular biology; Cell biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000225925,0.000511419,0.0002456115,0.0002983908,0.0001574726,0.0001980977,0.0003234204,0.0003925401,0.0008226897],"category_scores_gemma":[0.0001225393,0.0001709112,0.0003459087,0.0001248869,0.0002531486,0.0002035333,0.0003860274,0.0004613764,0.0004179179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002107839,"about_ca_system_score_gemma":0.0001717121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006444056,"about_ca_topic_score_gemma":0.001082006,"domain_scores_codex":[0.9998772,0.0000153225,0.00001280836,0.00004130294,0.00003580545,0.00001757833],"domain_scores_gemma":[0.9999012,0.00001633109,0.00004511646,0.00001393097,0.000008998387,0.00001440903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001188756,0.000007329299,0.00007101725,0.00004261577,0.00000332626,0.00007861395,0.00001868775,0.00009192489,0.9980819,0.0001349134,0.00002384813,0.001433992],"study_design_scores_gemma":[0.0000208522,0.0003284564,0.005006073,0.00001721639,0.00004367477,0.0009966171,0.00004313011,0.001922098,0.9863763,0.00009416655,0.005132476,0.00001892743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9636983,0.001132193,0.02961958,0.0001751416,0.00006609095,0.0001395168,0.0005333069,0.0005943417,0.004041564],"genre_scores_gemma":[0.9688421,0.001028498,0.02225136,0.00007118072,0.00001020979,0.0001125431,0.001044868,0.0001112386,0.006528028],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008226897,"threshold_uncertainty_score":0.002752185,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004960123797178067,"score_gpt":0.2443900259553705,"score_spread":0.2394299021581925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}