{"id":"W2795013773","doi":"10.1016/j.celrep.2018.03.017","title":"Serine Availability Influences Mitochondrial Dynamics and Function through Lipid Metabolism","year":2018,"lang":"en","type":"article","venue":"Cell Reports","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":257,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Serine; Ceramide; Biology; Cell biology; Biochemistry; Mitochondrion; Lipid metabolism; Sphingolipid; Glutamine; Amino acid; Apoptosis; Phosphorylation","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000926814,0.0001833356,0.0001497973,0.0001541419,0.0001259496,0.0002929631,0.0001059328,0.000156489,0.0009294505],"category_scores_gemma":[0.0001187627,0.00008303496,0.000116462,0.0001441775,0.0002136295,0.0002102107,0.0001780926,0.0002123922,0.0001539236],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002806896,"about_ca_system_score_gemma":0.0002199572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001022508,"about_ca_topic_score_gemma":0.001914172,"domain_scores_codex":[0.9999355,0.00001599041,0.00000706468,0.000011497,0.00001280593,0.00001717563],"domain_scores_gemma":[0.9999099,0.00001739629,0.00002653282,0.000008522623,0.00001216259,0.00002548383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002579698,0.00000475463,0.0004523645,0.0000173908,0.000003480011,0.00003543915,0.000008899785,0.00002288744,0.9983619,0.00003898084,0.0000113778,0.0007845716],"study_design_scores_gemma":[0.00001391355,0.0002494469,0.02491232,0.000007337968,0.00002014666,0.0002793782,0.00006325969,0.0004700882,0.9728813,0.00008889555,0.001008153,0.000005752946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965766,0.001697413,0.0006232495,0.00009518254,0.00001013681,0.000006279514,0.0002066995,0.00001599937,0.0007683977],"genre_scores_gemma":[0.9975857,0.001146717,0.0004534172,0.00002052105,0.000003540449,0.00000466775,0.0001801391,0.000004740375,0.0006005914],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001022508,"threshold_uncertainty_score":0.003109276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007456237411464011,"score_gpt":0.2337402650298185,"score_spread":0.2262840276183545,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}