{"id":"W2795043293","doi":"10.1093/schbul/sby015.188","title":"O1.6. INCREASED COMPLEMENT FACTORS C3 AND C4 IN SCHIZOPHRENIA AND THE EARLY STAGES OF PSYCHOSIS: IMPLICATIONS FOR CLINICAL SYMPTOMATOLOGY AND CORTICAL THICKNESS","year":2018,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Synaptic pruning; Psychosis; Schizophrenia (object-oriented programming); Complement system; Psychology; Neuroscience; Medicine; Immunology; Psychiatry; Immune system; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000318763,0.0002275316,0.0001834131,0.0005422493,0.0002527471,0.000342167,0.0001432228,0.0002089727,0.002542959],"category_scores_gemma":[0.0006920554,0.0001264661,0.0001421953,0.0004067855,0.0003905033,0.0001705493,0.000298343,0.0002252949,0.0001596424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002121651,"about_ca_system_score_gemma":0.0003162539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005415112,"about_ca_topic_score_gemma":0.005951791,"domain_scores_codex":[0.9998904,0.00002242306,0.000008918913,0.00003065203,0.00002399554,0.00002358552],"domain_scores_gemma":[0.9995465,0.00006741464,0.0002280019,0.00002482403,0.00005474153,0.00007861092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003850932,0.00007570748,0.8695402,0.0001292638,0.0001156296,0.0005765974,0.0006201924,0.0002150913,0.1098136,0.000204201,0.0001932825,0.0146653],"study_design_scores_gemma":[0.000005433837,0.0001134745,0.9973776,0.000004946913,0.00001334556,0.0003304317,0.0001221614,0.0001689439,0.001686873,0.00009097174,0.00008302851,0.000002804444],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991659,0.0001679271,0.0001528717,0.00001569078,0.000001549146,0.000004768467,0.0001206732,0.000003508504,0.0003671141],"genre_scores_gemma":[0.9993995,0.00005082298,0.0002271448,0.000005126319,0.000001571403,0.000003087425,0.00008073755,0.000002005393,0.0002300302],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005415112,"threshold_uncertainty_score":0.01076716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04318260919878247,"score_gpt":0.3332193710136783,"score_spread":0.2900367618148958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}