{"id":"W2795065690","doi":"10.1016/j.tetlet.2018.03.084","title":"Solid-phase synthesis of homodetic cyclic peptides from Fmoc-MeDbz-resin","year":2018,"lang":"en","type":"article","venue":"Tetrahedron Letters","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Population and Public Health; Inyuvesi Yakwazulu-Natali; Generalitat de Catalunya; King Saud University; National Research Foundation","keywords":"Chemistry; Cyclic peptide; Thiophenol; Cleavage (geology); Selectivity; Solid-phase synthesis; Side chain; Combinatorial chemistry; Amide; Stereochemistry; Peptide; Organic chemistry; Biochemistry; Catalysis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001680577,0.0004172515,0.0003318745,0.0002670061,0.0003001819,0.0002633887,0.0004441299,0.0002400384,0.006237371],"category_scores_gemma":[0.0001263545,0.0002292829,0.0002417414,0.000268328,0.0001402673,0.0002261381,0.0002489093,0.0006024996,0.002884036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003052075,"about_ca_system_score_gemma":0.0003915042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004471792,"about_ca_topic_score_gemma":0.001158177,"domain_scores_codex":[0.9998469,0.00001375944,0.00001034156,0.00003230645,0.00003420193,0.00006237102],"domain_scores_gemma":[0.9999167,0.00001492348,0.00001364786,0.00001596901,0.00001163845,0.00002712222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002636577,0.00007860207,0.00008911684,0.0001979479,0.00001250369,0.0001559972,0.00006168152,0.0004878711,0.9864205,0.001022981,0.0004836129,0.01072562],"study_design_scores_gemma":[0.00003053332,0.0002168926,0.0003441763,0.000007525522,0.000008130995,0.0001294083,0.0000181392,0.0005312113,0.9909114,0.0001307388,0.0076618,0.00001003908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9313811,0.002559801,0.04666824,0.0002575043,0.0001452517,0.0003528342,0.003992018,0.001139664,0.01350356],"genre_scores_gemma":[0.9449465,0.001511467,0.03865501,0.00009126247,0.00002887178,0.0001480667,0.002930064,0.0001979005,0.0114908],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006237371,"threshold_uncertainty_score":0.02086604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008282510833070455,"score_gpt":0.3004912076437609,"score_spread":0.2922086968106904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}