{"id":"W2795084380","doi":"10.1111/tra.12570","title":"Regulation of early endosomes across eukaryotes: Evolution and functional homology of Vps9 proteins","year":2018,"lang":"en","type":"article","venue":"Traffic","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Environmental Health Sciences; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Wellcome Trust","keywords":"Biology; Rab; Endocytic cycle; GTPase; Endocytosis; Cell biology; Endosome; Conserved sequence; Subfamily; Function (biology); Trypanosoma brucei; Genetics; Peptide sequence; Gene; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009405636,0.0000663107,0.00009420115,0.0000272156,0.00004121956,0.000002551714,0.00003456574,0.000112862,0.00003103326],"category_scores_gemma":[0.000009789704,0.00006547726,0.00004292424,0.00005930096,0.0002365402,0.000004220436,0.00001201273,0.00002962045,0.000001908822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004868516,"about_ca_system_score_gemma":0.00003019743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002173734,"about_ca_topic_score_gemma":0.00009791448,"domain_scores_codex":[0.9994893,0.00002064166,0.0001590874,0.0001542238,0.00007636459,0.0001003756],"domain_scores_gemma":[0.9996762,0.00000417382,0.00007689831,0.0001203928,0.00009941946,0.00002297243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002741326,0.00004303484,0.009758889,0.00002803345,0.00002191325,1.941848e-7,0.0002283865,0.000065006,0.9880923,0.0002373196,0.00001465338,0.001236159],"study_design_scores_gemma":[0.0006839218,0.0009882612,0.6409046,0.00001545173,0.00001928169,0.00001062042,0.00006661947,0.0002758099,0.3560821,0.0001268275,0.0007296722,0.0000968513],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867222,0.0003504241,0.0126132,0.00001842058,0.00007008267,0.0001282937,0.00001570928,0.000007149297,0.00007451397],"genre_scores_gemma":[0.9990637,0.00001719527,0.0002278068,0.000005345265,0.0001231177,0.000005498796,0.0003746735,0.000007162657,0.0001754615],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6320102,"threshold_uncertainty_score":0.2670085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01027646281919636,"score_gpt":0.2245558897229942,"score_spread":0.2142794269037978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}