{"id":"W2795131857","doi":"10.1093/schbul/sby017.726","title":"F195. ENRICHMENT OF PATHOGENIC VARIANTS ASSOCIATED WITH TREATABLE GENETIC DISEASES IN LARGE SCHIZOPHRENIA, BIPOLAR AND DEPRESSION COHORTS","year":2018,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Schizophrenia (object-oriented programming); Depression (economics); Bipolar disorder; Psychiatry; Medicine; Genetics; Clinical psychology; Biology; Cognition","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001161312,0.0004859021,0.0005069523,0.001142142,0.00106645,0.0009382497,0.0005025836,0.0006866637,0.006443436],"category_scores_gemma":[0.0039145,0.0002808039,0.001109227,0.001269997,0.000493395,0.0002401975,0.0005991446,0.000636347,0.0005066895],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002930011,"about_ca_system_score_gemma":0.0003965508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01652258,"about_ca_topic_score_gemma":0.01436059,"domain_scores_codex":[0.9988795,0.0002210104,0.0001108349,0.0004894906,0.0001568101,0.000142353],"domain_scores_gemma":[0.998046,0.0006322237,0.0007253287,0.0001979983,0.0001252862,0.0002731105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001263084,0.00003007677,0.9814152,0.00004806859,0.0008806434,0.001506518,0.0002614991,0.0001599183,0.005825643,0.0002312771,0.002139281,0.006238816],"study_design_scores_gemma":[0.00008335805,0.0000781211,0.9958261,0.00002347626,0.0003060721,0.001849764,0.0001333597,0.0004398328,0.000311444,0.0001963204,0.000739502,0.00001276513],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935272,0.0007607142,0.0007774828,0.0002888734,0.00005789678,0.0000189166,0.003273792,0.0000498302,0.00124543],"genre_scores_gemma":[0.998175,0.0001229636,0.000225131,0.000109117,0.00003028185,0.00001232957,0.001025937,0.00001931028,0.0002800046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01652258,"threshold_uncertainty_score":0.03285283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003729392513259533,"score_gpt":0.2022576637104421,"score_spread":0.1985282711971826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}