{"id":"W2795137969","doi":"10.1161/circulationaha.117.032636","title":"Cholesterol Efflux Pathways Suppress Inflammasome Activation, NETosis, and Atherogenesis","year":2018,"lang":"en","type":"article","venue":"Circulation","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":325,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Universiteit van Amsterdam; Rijksuniversiteit Groningen; York University; Universitair Medisch Centrum Groningen; National Center for Research Resources; University of Ottawa","keywords":"Medicine; Inflammasome; Efflux; Cholesterol; Cell biology; Inflammation; Immunology; Internal medicine; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003629742,0.0006815402,0.0006433942,0.0004279473,0.0001826621,0.0005612083,0.0002501567,0.000378768,0.003159788],"category_scores_gemma":[0.0002394297,0.0001888864,0.0002999951,0.000191623,0.0004282654,0.0003226281,0.0002998201,0.0009793404,0.0006165354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002963284,"about_ca_system_score_gemma":0.0003416935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002033723,"about_ca_topic_score_gemma":0.0005872225,"domain_scores_codex":[0.9998316,0.00003144981,0.0000192207,0.00002465124,0.00003521587,0.00005793891],"domain_scores_gemma":[0.9997506,0.00001907609,0.0001169844,0.00002386075,0.00002067874,0.00006870974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006680795,0.001058479,0.001049407,0.0004238888,0.00008229277,0.0001559032,0.00003546155,0.0001743972,0.9767358,0.0003532598,0.0007887696,0.01246159],"study_design_scores_gemma":[0.006672975,0.01670261,0.02052431,0.0001060733,0.0004303986,0.00148968,0.0001199786,0.001992546,0.933341,0.0008460567,0.01773435,0.0000400532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871902,0.007473785,0.001434443,0.0007701879,0.000163486,0.0001584305,0.0004935695,0.0002748578,0.002041051],"genre_scores_gemma":[0.9913225,0.003572169,0.001373322,0.0003330677,0.0001125167,0.0001931196,0.0006501155,0.00004467281,0.00239865],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003159788,"threshold_uncertainty_score":0.01057053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009581525615327987,"score_gpt":0.2190161140785476,"score_spread":0.2094345884632196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}