{"id":"W2795208446","doi":"10.1155/2018/8431053","title":"Production of Adult Human Synovial Fluid-Derived Mesenchymal Stem Cells in Stirred-Suspension Culture","year":2018,"lang":"en","type":"article","venue":"Stem Cells International","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Bone and Joint Health Institute; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Innovates; Alberta Innovates - Health Solutions","keywords":"Microcarrier; Laboratory flask; Bioreactor; Mesenchymal stem cell; Bioprocess; Chondrogenesis; Synovial fluid; Cell biology; Cell culture; Tissue engineering; Stem cell; Biomedical engineering; Chemistry; Cell; Biology; Medicine; Pathology; Biochemistry; Osteoarthritis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006956238,0.0004754096,0.000526591,0.0004049563,0.0002251725,0.0006002448,0.0003463046,0.0003326128,0.001054084],"category_scores_gemma":[0.0003144538,0.0001650765,0.0005071292,0.0004672213,0.0002004354,0.0002206539,0.0003655874,0.0005618262,0.001254853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002553331,"about_ca_system_score_gemma":0.0003771877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008887703,"about_ca_topic_score_gemma":0.001246243,"domain_scores_codex":[0.9996771,0.00005422035,0.00005767858,0.00005692957,0.0001208329,0.00003330193],"domain_scores_gemma":[0.999796,0.00003861613,0.00003874358,0.00003353163,0.00005620243,0.00003694023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000131016,0.00005451056,0.0003258066,0.00008280671,0.000008011697,0.00007135281,0.00005819994,0.0003329008,0.9934316,0.0001337997,0.00009170065,0.005278229],"study_design_scores_gemma":[0.00002947472,0.0004539288,0.00103185,0.00001449345,0.00004245772,0.0001368765,0.00002858595,0.001978807,0.9921079,0.00007601547,0.004089858,0.000009773279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7504734,0.008814577,0.2244277,0.000291298,0.0004991062,0.001468702,0.0034299,0.001399272,0.009196013],"genre_scores_gemma":[0.8730496,0.003105511,0.1121217,0.0001114289,0.0001334821,0.0004672303,0.004016615,0.0001011471,0.006893272],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001054084,"threshold_uncertainty_score":0.003678918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01544525304082584,"score_gpt":0.2632426333286748,"score_spread":0.2477973802878489,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}