{"id":"W2795226545","doi":"10.1002/glia.23333","title":"<scp>T</scp>he extracellular matrix: <scp>F</scp>ocus on oligodendrocyte biology and targeting <scp>CSPG</scp>s for remyelination therapies","year":2018,"lang":"en","type":"review","venue":"Glia","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Multiple Sclerosis Society of Canada; Canadian Institutes of Health Research; Alberta Innovates - Health Solutions","keywords":"Remyelination; Oligodendrocyte; Biology; Myelin; Extracellular matrix; Cell biology; Neuroscience; Regeneration (biology); Multiple sclerosis; Central nervous system; Extracellular; Chondroitin sulfate proteoglycan; Immunology; Proteoglycan","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002477593,0.0004747079,0.0004285362,0.001394602,0.0002257114,0.0005984135,0.0004015216,0.0006421896,0.005602545],"category_scores_gemma":[0.0003628589,0.0001148311,0.0002427531,0.001273184,0.0002808537,0.0007732991,0.0004636562,0.001023033,0.002655789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004122382,"about_ca_system_score_gemma":0.0007270565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008816347,"about_ca_topic_score_gemma":0.001651668,"domain_scores_codex":[0.9999133,0.00001165345,0.00001033576,0.00001287678,0.00003965744,0.00001202939],"domain_scores_gemma":[0.9998713,0.0000402058,0.00002013852,0.000005517556,0.00004177709,0.0000211082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007414453,0.00005519368,0.0001347387,0.01139946,0.00005048326,0.0002396082,0.00005177076,0.0002797604,0.009262237,0.006558464,0.04579318,0.926101],"study_design_scores_gemma":[0.000004641614,0.0000357814,0.0004330593,0.001211927,0.0000257855,0.0007467661,0.00002477421,0.0000513284,0.001521499,0.001045121,0.9948925,0.000006864658],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004752461,0.9922922,0.0003535065,0.000592747,0.0006322987,0.000008877631,0.00005438105,0.00002245149,0.005568261],"genre_scores_gemma":[0.001952041,0.9932247,0.0003382484,0.0002968378,0.0002578195,0.000008456994,0.00007170087,0.000004188548,0.003846077],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005602545,"threshold_uncertainty_score":0.01874238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03069338462243289,"score_gpt":0.3420920818274397,"score_spread":0.3113986972050068,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}