{"id":"W2795439944","doi":"10.1093/annonc/mdy115","title":"Should decisions on adding adjuvant chemotherapy in early-stage ER-positive breast cancer be based on gene expression testing or clinicopathologic factors or both?","year":2018,"lang":"en","type":"letter","venue":"Annals of Oncology","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Breast cancer; Oncology; Internal medicine; Tamoxifen; Clinical trial; Cancer; Adjuvant therapy; Hormonal therapy; Chemotherapy; Stage (stratigraphy); Randomized controlled trial; Adjuvant; Gynecology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02524632,0.00080294,0.004785967,0.002545201,0.0008586429,0.004152099,0.002842104,0.006989401,0.01192278],"category_scores_gemma":[0.1378416,0.0005904821,0.003233316,0.002972518,0.002416539,0.006252632,0.001451101,0.009009485,0.006454805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002859494,"about_ca_system_score_gemma":0.004275951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004689757,"about_ca_topic_score_gemma":0.01292567,"domain_scores_codex":[0.9886826,0.007080692,0.001697082,0.0008134545,0.001355028,0.0003711546],"domain_scores_gemma":[0.9257954,0.05423567,0.006536795,0.001736889,0.008350457,0.0033448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01112044,0.0005690387,0.02128071,0.007360293,0.002168564,0.0003948904,0.000543565,0.001405658,0.0009963472,0.007593075,0.4034254,0.543142],"study_design_scores_gemma":[0.0104631,0.003207515,0.05858974,0.07729812,0.009875533,0.001430374,0.003944029,0.004861344,0.002628469,0.2126079,0.614228,0.0008659065],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01500252,0.2020757,0.003592407,0.7456139,0.01523243,0.000319189,0.003265522,0.0001234335,0.01477491],"genre_scores_gemma":[0.22646,0.1961497,0.03492912,0.4838299,0.04714542,0.001169712,0.003873162,0.0002924202,0.006150666],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02524632,"threshold_uncertainty_score":0.1335169,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1989915160118517,"score_gpt":0.4224964227929147,"score_spread":0.223504906781063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}